TRPC3 regulates the automaticity of embryonic stem cell-derived cardiomyocytes
Z Qi, CK Wong, CH Suen, J Wang, C Long… - International journal of …, 2016 - Elsevier
… Taken together with the finding that TRPC3 positively regulated the LCR, we speculate that
Ca 2 + influx through TRPC3, through increasing the LCR, drives the forward mode of NCX, …
Ca 2 + influx through TRPC3, through increasing the LCR, drives the forward mode of NCX, …
[HTML][HTML] Ca 2+/Calmodulin-dependent kinase II delta B is essential for cardiomyocyte hypertrophy and complement gene expression after LPS and HSP60 stimulation …
CV Cruz Junho, M Trentin-Sonoda, JM Alvim… - Brazilian Journal of …, 2019 - SciELO Brasil
… the nuclear translocation of nuclear factor-kappa B (NF-κB). Despite the importance of
the complement system in CVDs, only a few studies have examined the role of … Ca2+/calmodulin-…
the complement system in CVDs, only a few studies have examined the role of … Ca2+/calmodulin-…
Genetic inhibition of nuclear factor of activated T-cell c2 prevents atrial fibrillation in CREM transgenic mice
… Ca 2+ -dependent hypertrophic pathway involving nuclear factor of activated T-cell (NFAT)/regulator
of calcineurin 1-4 (Rcan1-4) signalling, suggesting a role … atrial cardiomyocytes was …
of calcineurin 1-4 (Rcan1-4) signalling, suggesting a role … atrial cardiomyocytes was …
[HTML][HTML] Alkaline nucleoplasm facilitates contractile gene expression in the mammalian heart
A Hulikova, KC Park, AA Loonat… - Basic Research in …, 2022 - Springer
… by transcriptomics of neonatal cardiomyocytes cultured over a … We also characterised the
relationship between nuclear and … stimulation at 0.8, 2 or 4 Hz to load Ca 2+ stores. To produce …
relationship between nuclear and … stimulation at 0.8, 2 or 4 Hz to load Ca 2+ stores. To produce …
… H9c2 cardiomyocytes against oxygen-glucose deprivation/reoxygenation-induced intracellular calcium overload and apoptosis through regulating FKBP12. 6/RyR2 …
M Yuan, XW Meng, J Ma, H Liu, SY Song… - Drug design …, 2019 - Taylor & Francis
… on Ca 2+ signaling and apoptosis in H9c2 cardiomyocytes … differentiation primary response
88-nuclear factor-kappa B via … activation induced Ca 2+ leakage via regulating FKBP12.6 …
88-nuclear factor-kappa B via … activation induced Ca 2+ leakage via regulating FKBP12.6 …
Rg3 promotes the SUMOylation of SERCA2a and corrects cardiac dysfunction in heart failure
Z Liu, X Bian, W Gao, J Su, C Ma, X Xiao, T Yu… - Pharmacological …, 2021 - Elsevier
… Ca 2+ homeostasis in heart failure has not been reported. In this study, we showed a novel
role of Rg3 in the abnormal Ca 2+ cycle in cardiomyocytes … /nuclear transfer, regulates …
role of Rg3 in the abnormal Ca 2+ cycle in cardiomyocytes … /nuclear transfer, regulates …
[HTML][HTML] TRPC5-eNOS axis negatively regulates ATP-induced cardiomyocyte hypertrophy
… These ligands can induce hypertrophic growth of neonatal rat cardiomyocytes (NRCMs)
mainly through Ca 2+ -dependent calcineurin/nuclear factor of activated T cell (NFAT) signaling …
mainly through Ca 2+ -dependent calcineurin/nuclear factor of activated T cell (NFAT) signaling …
[HTML][HTML] Hypertrophy of human embryonic stem cell–derived cardiomyocytes supported by positive feedback between Ca2+ and diacylglycerol signals
C Deisl, M Fine, OW Moe, DW Hilgemann - Pflügers Archiv-European …, 2019 - Springer
… Local Ca 2+ signals generated by IP 3 -dependent Ca 2+ release at the nuclear envelope
… That DAG signaling plays a key role in the initiation of hypertrophy is demonstrated, for …
… That DAG signaling plays a key role in the initiation of hypertrophy is demonstrated, for …
Physiological and pathological roles of protein kinase A in the heart
… at the plasma membrane to regulate L-type Ca 2+ channel (… (SR) to modulate the functions
of ryanodine receptors (RyRs) … cardiomyocyte hypertrophy through inhibition of nuclear PKA …
of ryanodine receptors (RyRs) … cardiomyocyte hypertrophy through inhibition of nuclear PKA …
Computational modeling approaches to cAMP/PKA signaling in cardiomyocytes
KJ McCabe, P Rangamani - Journal of molecular and cellular cardiology, 2021 - Elsevier
… ) to track nuclear PKA activity, and it was found that nuclear PKA … in the cardiomyocyte
contain information about Ca 2+ … of various Ca 2+ channels and the Ca 2+ transient at large, …
contain information about Ca 2+ … of various Ca 2+ channels and the Ca 2+ transient at large, …