… (MAPK) and to the consequent nuclear translocation of the cardiac transcription factor, the
… and inactivation of Ca v 1.2 play a key role in regulating the magnitude of Ca 2+ influx [175]. …

… Ca 2+ signaling and for refilling depleted Ca 2+ stores. The role of SOCE in cardiomyocytes,
… evidence for increased Ca 2+ influx into cardiomyocytes following Ca 2+ store depletion, it …

… ) play important roles in regulating cardiomyocyte physiology, … can cause functional alterations
in the overall inward Ca 2+ … Consistent with a direct role of nuclear Ca v β2 in regulating …

… + , which in turn dephospholylates the transcription factor NFAT (nuclear factor of activated
… the role of AKAP150 in regulating Ca 2+ regulatory proteins in cardiomyocytes under basal …

… + /calmodulin-dependent protein kinase II (CaMKII) and nuclear … Their activities are regulated
by intracellular Ca 2+ . We … cardiomyocyte apoptosis via suppressing intracellular Ca 2+ …

… Nuclear activity in cardiac myocytes is strongly regulated by … Indeed, maneuvers that alter
nuclear Ca 2 + signaling can stably change ΔpH, and we hypothesize that this may involve the …

… nuclear envelope-bridging interactions with inner nuclear … kinase 1 (SIK1), and Ca 2+ /calmodulin-dependent
kinases … PKA and PKD is regulated in cardiac myocytes by mAKAPβ …

… cardiomyocyte nuclear AT1Rs are coupled to IP3R activation to increase nuclear Ca 2+
concentration [Ca 2… , respectively, of nuclear AT1R and AT2R activation to nuclear Ca 2+ and NO …

… and regulated nuclear Ca 2+ signalling microdomains independent of cytosolic Ca 2+ release,
nuclear-specific expression of either Ca 2… remodelling in isolated cardiomyocytes [39,72]. …

… Cardiomyocytes contain a small but measurable pool of … role of Zn 2+ in regulating diastolic
Ca 2+ leak is poorly characterized. Here we examine the role of Zn 2+ in shaping SR Ca 2+ …