Mechanistic insights from structural analyses of Ran-GTPase-driven nuclear export of proteins and RNAs

Y Matsuura - Journal of molecular biology, 2016 - Elsevier
… -dependent nuclear transport factors that belong to the karyopherin-β family and mediate
nuclear export of a plethora of proteins and RNAs, except for bulk mRNA nuclear export. …

Mechanisms of RNA export and nuclear retention

M Khan, S Hou, M Chen, H Lei - … Interdisciplinary Reviews: RNA, 2023 - Wiley Online Library
nuclear retention of ncRNA. This review aims to summarize the recent findings from studies
on the mechanisms of export of different RNAs and nuclear … for the export of spliced mRNA …

RNA nuclear export: from neurological disorders to cancer

GM Hautbergue - … Medicine: Lessons from Neurodegeneration to Cancer, 2017 - Springer
proteins such as the polymeric repeat proteins produced in some neurodegenerative
diseases. Alterations of the mRNA nuclear export … driving the nuclear export of RNAs with a …

Strength in diversity: nuclear export of viral RNAs

JP Gales, J Kubina, A Geldreich, M Dimitrova - Viruses, 2020 - mdpi.com
… and are efficiently exported for … nuclear export mechanisms and presents detailed insights
into the most important strategies that viruses use to export the different forms of their RNAs

Polyadenylation and nuclear export of mRNAs

M Stewart - Journal of Biological Chemistry, 2019 - ASBMB
… mRNA nuclear export and how it is integrated into the nuclear phase of the gene expression
pathway. Nuclear export … , such as proteins and RNAs, between the cytoplasmic and nuclear

Controlling nuclear RNA levels

M Schmid, TH Jensen - Nature Reviews Genetics, 2018 - nature.com
… Whereas the cytoplasmic control of protein-coding mRNA is often … of nuclear RNA decay
systems in controlling RNA polymerase II (RNAPII)-derived transcripts. Historically, nuclear RNA

Sequence determinants for nuclear retention and cytoplasmic export of mRNAs and lncRNAs

AF Palazzo, ES Lee - Frontiers in genetics, 2018 - frontiersin.org
… recruit export factors to the mature RNA, nuclear export does … are well exported and associate
with these same export factors … RNA is a substrate for nuclear export unless it contains a …

Nuclear export of circular RNA

LH Ngo, AG Bert, BK Dredge, T Williams, V Murphy… - Nature, 2024 - nature.com
… To search for proteins that are required for the nuclear export of circRNAs, we depleted
candidate proteins that are known to be involved in export of different subtypes of RNA and …

New progresses of circular RNA biology: from nuclear export to degradation

M Zhou, MS Xiao, Z Li, C Huang - RNA biology, 2021 - Taylor & Francis
… Once produced in the nucleus, the majority of circular RNAs are exported to the cytoplasm …
RNAs and highlight the recent advances in our understanding of circular RNA nuclear export

Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA

AC Woerner, F Frottin, D Hornburg, LR Feng… - Science, 2016 - science.org
… a nuclear export sequence (NES) or nuclear localization … the nuclear translocation of the
endogenous protein nuclear … cells and in cells expressing nuclear β-sheet proteins. In contrast, …