Identification of Osr2 transcriptional target genes in palate development

X Fu, J Xu, P Chaturvedi, H Liu… - Journal of dental …, 2017 - journals.sagepub.com
intrinsic regulator of palatal shelf growth and morphogenesis… the odd-skipped related 2
(Osr2) transcription factor as a key … of Smoothened, which encodes an obligatory transducer of …

YAP/TAZ regulate elevation and bone formation of the mouse secondary palate

AF Goodwin, CP Chen, NT Vo… - Journal of Dental …, 2020 - journals.sagepub.com
… of YAP/TAZ in secondary palate development by disrupting their … with the Osr2 Cre driver,
the PSs appeared similar in the Yap … Ibsp, which encodes a major protein component of bone, …

[HTML][HTML] Gene regulatory networks and signaling pathways in palatogenesis and cleft palate: a comprehensive review

HJ Won, JW Kim, HS Won, JO Shin - Cells, 2023 - mdpi.com
… The secondary palate develops as paired protrusions that growOdd-skipped related 2
(Osr2) is decreased in the palatal … Osr1 and Osr2 are zinc-finger transcription factor encoding

Revisiting the embryogenesis of lip and palate development

NL Hammond, MJ Dixon - Oral Diseases, 2022 - Wiley Online Library
… during secondary palate development and imply … Odd-skipped-related 2 is an intrinsic
regulator of palatal mesenchymal cell proliferation with Osr2 −/− mice displaying cleft palate

The Function and Regulatory Network of Pax9 Gene in Palate Development

R Li, Z Chen, Q Yu, M Weng… - Journal of dental …, 2019 - journals.sagepub.com
… genes (Osr2 and Bmpr1a) leading to deficient palate growth, … between PAX9 and genes
encoding the OSR2, TGFβ3, and … PAX9 might participate in the regulation of palate fusion. This …

Downregulation of odd-skipped related 2, a novel regulator of epithelial-mesenchymal transition, enables efficient somatic cell reprogramming

LPH Anh, K Nishimura, A Kuno, NT Linh, T Kato… - Stem Cells, 2022 - academic.oup.com
… that acts through induction of transforming growth factor-β (TGF… that downregulation of
odd-skipped related 2 (Osr2) is crucial … Mouse Osr2 gene encodes a zinc-finger protein related to …

[HTML][HTML] Six2 Plays an Intrinsic Role in Regulating Proliferation of Mesenchymal Cells in the Developing Palate

DO Okello, PPR Iyyanar, WM Kulyk, TM Smith… - Frontiers in …, 2017 - frontiersin.org
secondary palate (SP) formation. The Sine oculis-related homeobox 2 (Six2) gene has been
linked to … The possibility that Six2 plays a specific role in SP development has not been …

[HTML][HTML] A Shh-Foxf-Fgf18-Shh molecular circuit regulating palate development

J Xu, H Liu, Y Lan, BJ Aronow, VV Kalinichenko… - PLoS …, 2016 - journals.plos.org
… The mammalian secondary palate develops from the oral side of … encodes a member of the
fibroblast growth factor family ligands, was up-regulated by more than 2-fold in Foxf2 -/- Osr2

[HTML][HTML] Bmp4-Msx1 signaling and Osr2 control tooth organogenesis through antagonistic regulation of secreted Wnt antagonists

S Jia, HJE Kwon, Y Lan, J Zhou, H Liu, R Jiang - Developmental Biology, 2016 - Elsevier
… We recently demonstrated that deletion of Osr2, which encodes a zinc finger transcription …
underlying the antagonistic regulation of tooth development by Msx1 and Osr2, we carried …

[HTML][HTML] Spatiotemporal Gene Expression Regions along the Anterior–Posterior Axis in Mouse Embryos before and after Palatal Elevation

A Nagasaka, K Sakiyama, Y Bando… - International Journal of …, 2022 - mdpi.com
… The mammalian secondary palate is formed through complex developmental processes: …
of the Drosophila odd-skipped family developmental regulators [22,23]. Osr2 was expressed …