[PDF][PDF] The role of brain-derived neurotrophic factor (BDNF) in cognitive functions

D Silakarma, AAR Sudewi - Bali Medical Journal, 2019 - pdfs.semanticscholar.org
… affinity binding by NT-3, and trkC binds NT-3. Trk receptors … of BDNF mRNA in the hippocampus
and cerebral cortex. However, … The provision of BDNF or increasing endogenous BDNF

Neurotrophin-3 modulates synaptic transmission

E Hernández-Echeagaray - Vitamins and hormones, 2020 - Elsevier
… This chapter focuses role of NT-3 in the modulation of … shown to control axonal and dendritic
development as well as … demonstrated that NT-3 and BDNF locally regulated synaptic …

Targeting neurotrophins to specific populations of neurons: NGF, BDNF, and NT-3 and their relevance for treatment of spinal cord injury

KM Keefe, IS Sheikh, GM Smith - International journal of molecular …, 2017 - mdpi.com
… help with the growth of CST … dendrites of corticospinal motor neurons, but not on their
descending axons [4]. Neuroprotective effects of BDNF were also seen in the primary motor cortex

Cell type-specific effects of BDNF in modulating dendritic architecture of hippocampal neurons

M Zagrebelsky, N Gödecke, A Remus… - Brain Structure and …, 2018 - Springer
… to BDNF for different hippocampal and cortical neuronal … of endogenous BDNF under culture
conditions. We therefore … indicate that BDNF regulates dendritic development and synaptic …

Is neurotrophin-3 (NT-3): a potential therapeutic target for depression and anxiety?

AS de Miranda, JLVM de Barros… - Expert Opinion on …, 2020 - Taylor & Francis
Endogenous BDNF and NT3 exhibit opposite actions in regulating dendritic growth of
pyramidal neurons from layers 4 and 6 of the developing ferret visual cortex [Citation71]. …

Neurotrophins and proneurotrophins: focus on synaptic activity and plasticity in the brain

J Gibon, PA Barker - The Neuroscientist, 2017 - journals.sagepub.com
… and mature neurotrophins exerts opposing role in the central … on the role of the Val66Met
polymorphism on the BDNF … In hippocampal neurons, NT-3 binding to TrkC allows this receptor …

Opposing presynaptic roles of BDNF and ProBDNF in the regulation of persistent activity in the entorhinal cortex

J Gibon, PA Barker, P Séguéla - Molecular brain, 2016 - Springer
… whether this activity is regulated by other endogenous neuromodulators remains unknown.
BDNF and proBDNF play opposite roles in the regulation of PF in cortical pyramidal neurons. …

[HTML][HTML] Regulation of neurogenesis by neurotrophins during adulthood: expected and unexpected roles

M Vilar, H Mira - Frontiers in neuroscience, 2016 - frontiersin.org
dendritic abnormalities similar to those observed in conditional knockout mice in which BDNF
… normal dendritic development in adult-born cells of BDNF conditional knockouts in which …

The role of dendritic brain-derived neurotrophic factor transcripts on altered inhibitory circuitry in depression

H Oh, SC Piantadosi, BR Rocco, DA Lewis… - Biological …, 2019 - Elsevier
… L-3′-UTR knockdown is sufficient to induce 1) dendritic shrinkage in cortical neurons, 2)
cell-specific MDD-like gene changes (including Sst downregulation), and 3) depressive- and …

[PDF][PDF] Transient deregulation of canonical wnt signaling in developing pyramidal neurons leads to dendritic defects and impaired behavior

B Viale, L Song, V Petrenko, ALW Combremont… - Cell reports, 2019 - cell.com
dendritic growth period (E21–P7), the thalamocortical inputs … regulation plays a role in
dendritic maturation of layer II … of other neurotrophins (eg, BDNF). Previous studies suggested …