[PDF][PDF] Organoid-based single-cell spatiotemporal gene expression landscape of human early embryonic development and hematopoiesis
RR Sugimura - Cold Spring Harbor meeting on Gene Expression & …, 2022 - hub.hku.hk
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[HTML][HTML] Organoid-based single-cell spatiotemporal gene expression landscape of human embryonic development and hematopoiesis
The cell-cell interactions are fundamental mechanisms of differentiating embryonic tissues. 1
We aimed to model human embryonic development in stem-cell-derived organoids. We
exploited the time series single-cell and spatial transcriptomics to reveal the gene
expression landscape in the development of embryonic tissues and their interactions. We
leveraged the Human EMbryonic Organoid (HEMO) to model the development of embryonic
tissues from human pluripotent stem cells proficient in both the extra-embryonic lineage and …
We aimed to model human embryonic development in stem-cell-derived organoids. We
exploited the time series single-cell and spatial transcriptomics to reveal the gene
expression landscape in the development of embryonic tissues and their interactions. We
leveraged the Human EMbryonic Organoid (HEMO) to model the development of embryonic
tissues from human pluripotent stem cells proficient in both the extra-embryonic lineage and …
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