Invasiveness of the Yersinia pestis ail protein contributes to host dissemination in pneumonic and oral plague

Y Zhang, X Ying, Y He, L Jiang, S Zhang, SS Bartra… - Microbial …, 2020 - Elsevier
pestis expresses the outer membrane protein, Ail (Attachment invasion locus), which is …
colleagues demonstrated that Y. pestis Ail contributes to the virulence of pneumonic plague [35] …

Structural Insights into the Yersinia pestis Outer Membrane Protein Ail in Lipid Bilayers

SK Dutta, Y Yao, FM Marassi - The Journal of Physical Chemistry …, 2017 - ACS Publications
Ail is essential for microbial virulence and is critical for … Structures of Ail have been
determined by X-ray diffraction and … antibiotic resistance, all contribute to the classification of Y. …

[HTML][HTML] Yersinia pestis and plague: an updated view on evolution, virulence determinants, immune subversion, vaccination, and diagnostics

CE Demeure, O Dussurget, G Mas Fiol… - Genes & …, 2019 - nature.com
… encoded Ail outer-membrane protein contributes to cell … , and in a murine model of pneumonic
plague [64]. In the same … -inflammatory phase: cell membrane rupture leads to bacterial …

Interaction between Yersinia pestis Ail Outer Membrane Protein and the C-Terminal Domain of Human Vitronectin

L Vasseur, F Barbault, A Monari - The Journal of Physical …, 2024 - ACS Publications
… In this contribution, … contribution, yet our work enhances significantly the knowledge of the
intricate coupling between human circulating proteins and bacteria in increasing the virulence

[HTML][HTML] Yersinia Outer Membrane Vesicles as Potential Vaccine Candidates in Protecting against Plague

AA Byvalov, IV Konyshev, VN Uversky… - Biomolecules, 2020 - mdpi.com
… Each of these antigens contributes relatively little to … animals infected with virulent strains of
the plague pathogen. … to the group of extracellular or outer membrane proteins [150]. It can be …

Pneumonic Plague Protection Induced by a Monophosphoryl Lipid A Decorated Yersinia OuterMembrane‐Vesicle Vaccine

S Majumder, S Das, P Li, N Yang, H Dellario, H Sui… - Small, 2024 - Wiley Online Library
… history caused by Yersinia pestis. [ 1 ] In the present era, … may contribute to remarkable
protection against pneumonic … To achieve respiratory protection against fully virulent Y. …

[HTML][HTML] Yersinia pestis and Plague: Some knowns and unknowns

…, P Slavin, Y Song, Y Yan, Y Wu… - Zoonoses (Burlington …, 2023 - ncbi.nlm.nih.gov
contributes to virulence in naturally acquired bubonic plague but is not essential for pneumonic
plague in … Ail is a chromosomally encoded small-membrane protein common to all three …

Immunology of Yersinia pestis Infection

Y Bi - Yersinia pestis: retrospective and perspective, 2016 - Springer
… ) is a major component of the outer membrane in Gram-negative … and contributed to
LcrV-mediated plague pathogenesis [87]. In … pestis virulence-associated proteins, we screened the …

[PDF][PDF] Novel Virulence Factors in the Pathogenesis of Yersinia pestis Infection, the Causative Agent of Plague

EC Fitts - 2018 - utmb-ir.tdl.org
… by deletion of other virulence factors leads to avirulence, F1 … pestis virulence during both
bubonic and pneumonic plague, … Similarly, an outer membrane protein Ail which provides …

Pathology and Pathogenesis of Yersinia pestis

Z Du, X Wang - Yersinia pestis: Retrospective and Perspective, 2016 - Springer
contribute to the unique pathogenicity and transmission of Y. … It belongs to the Ail/Lom
outer membrane protein family that … in virulence in bubonic and pneumonic plague infection …