Polyethyleneimine-based drug delivery systems for cancer theranostics

C Zhao, B Zhou - Journal of Functional Biomaterials, 2022 - mdpi.com
… and challenges relating to PEI-based drug delivery systems. … The PEI-grafted chitosan
significantly reduced the toxicity of … , intracellular gene delivery was also interrupted by longer PEG

Folic acid decorated chitosan nanoparticles and its derivatives for the delivery of drugs and genes to cancer cells

AA John, SK Jaganathan, M Ayyar, NP Krishnasamy… - Current Science, 2017 - JSTOR
… on tumour-targeted drug delivery using folate-chitosan nanoparticles (FA-CS NPs) for … than
the 25 kDa PEI and CHI-g-PEI. FA-PEG CHI-g-PEI displayed enhanced transfection efficiency …

Polyethylenimine-based nanocarriers in co-delivery of drug and gene: a developing horizon

A Zakeri, MAJ Kouhbanani… - Nano reviews & …, 2018 - Taylor & Francis
PEI as an appropriate vector for the effective gene delivery. … (PEG) shielding strategy
for gene delivery system in cancer … of PEI-coated with chitosan and modified with arginine …

Targeted magnetic iron oxide nanoparticles: Preparation, functionalization and biomedical application

AA Abd Elrahman, FR Mansour - … of Drug Delivery Science and Technology, 2019 - Elsevier
… Di-block copolymers such as PEO-PMAA (Polyethylene oxide with Polymethyl methacrylate),
PAA-chitosan (Polyacrylic acid with chitosan), and PEG-PLGA (polyethylene glycol with …

Chitosan‐based nanocarriers for gene delivery

HN Abdelhamid - Nanoengineering of Biomaterials, 2022 - Wiley Online Library
… (PEG) [65] were used for the modification of chitosan. Chitosan was grafted with PEG, CH-g-PEI,
for the deliveryPEI-g-chitosan, a novel gene delivery system with transfection efficiency …

Exploring modified chitosan-based gene delivery technologies for therapeutic advancements

AD Gholap, HS Kapare, S Pagar, P Kamandar… - International Journal of …, 2024 - Elsevier
gene therapy is the successful delivery of the genes. Immunogenicity and toxicity are major
issues for viral gene delivery … like chitosan could be used as a nonviral gene delivery vector …

A review on the application of nanoparticles for targeted gene delivery

S Moniri Javadhesari, M Jabraili, M Koohi - Advanced Ceramics Progress, 2022 - acerp.ir
… in gene transfer, and the transfection efficacy of 25 kDa PEI … adsorption of DNA/RNA to
IONPs (iron oxide NPs) [28]. 4.1. … polymer PEG-b-PLGA, lipid-based NPs, chitosan, and PEI or …

Gene delivery of chitosan-graft-polyethyleneimine vectors loaded on scaffolds for nerve regeneration

Y Wang, Y Li, Z Huang, B Yang, N Mu, Z Yang… - Carbohydrate …, 2022 - Elsevier
chitosan-graft-polyethyleneimine (RCP) gene vectors were prepared, through grafting the
branched PEI (lower molecular weight, 600 Da) on CS, to enhance PEI capacity for binding …

Study on doxorubicin loading on differently functionalized iron oxide nanoparticles: implications for controlled drug-delivery application

VR Khabibullin, MR Chetyrkina, SI Obydennyy… - International Journal of …, 2023 - mdpi.com
… of the effects of IONs coated with PSS and PEI on the rate of blood … into account when
developing new drug delivery platforms. … The polymer coating based on polyethylene glycol (PEG) …

Iron oxide nanoparticles decorated with functional peptides for a targeted siRNA delivery to glioma cells

S Chung, Y Sugimoto, J Huang… - ACS Applied Materials & …, 2022 - ACS Publications
… -chitosan-PEG-PEI copolymer. The catechol group, which has high affinity for iron, increases
the stability of the nanoparticle … between the polymer coating and the iron oxide core. The …