Nanotechnology in drug and gene delivery

S Hamimed, M Jabberi, A Chatti - Naunyn-schmiedeberg's Archives of …, 2022 - Springer
… as PEG, chitosan, and collagen, which seal the drug molecule … encapsulated
superparamagnetic iron oxide nanoparticles (… Also, biopolymer such as chitosan for drug delivery

Nonviral gene therapy: design and application of inorganic nanoplexes

MV Panizo, A Domínguez-Bajo, MT Portolés… - Nucleic Acid …, 2019 - Elsevier
… to improve the SPIONs-chitosan gene delivery in a synergic effect… realized that iron oxide-based
carriers for gene delivery had the … In combination with PEI, PEG has also been used to …

Iron Oxide Nanoparticle-Mediated mRNA Delivery to Hard-to-Transfect Cancer Cells

J Huang, G Lin, T Juenke, S Chung, N Lai, T Zhang… - Pharmaceutics, 2023 - mdpi.com
… Unlike DNA delivery, mRNA delivery does not require host … an iron oxide core coated with
chitosan-PEG copolymer modified with catechol, while IOCCP-2k/25k PEI is similar but coated

EDTA‐Capped Iron Oxide Core‐Corona System as Vehicle for Gene Delivery to Transform E.coli: Mimicking the Lipid Bilayer Environment

E Shah, A Kadam, T Jubin, R Begum… - …, 2019 - Wiley Online Library
… and its block copolymer with polyethylene glycol (PLL-b-PEG),16 −20 poly ethyleneimine
(PEI),… Carbohydrate polymers such as chitosan and poly-β-cyclodextrin29 −32 have also been …

Recent advances in polymer-coated iron oxide nanoparticles as magnetic resonance imaging contrast agents

M Salehipour, S Rezaei, J Mosafer… - Journal of Nanoparticle …, 2021 - Springer
… of magnetic iron oxide nanoparticles have been … therapy, targeted drug or gene delivery,
tissue engineering, and cell separation (Boyer et al. 2010). Magnetic iron oxide nanoparticle

Recent progress in nanomaterials for gene delivery applications

E Keles, Y Song, D Du, WJ Dong, Y Lin - Biomaterials science, 2016 - pubs.rsc.org
… , chitosan, has promising applications in gene delivery because … in gene delivery requires
modifications such as PEG … decreasing cytotoxicity in gene delivery compared to bare PEI NPs. …

Polymeric nanoparticle-based drug/gene delivery for lung cancer

L Ray - Nanotechnology-Based Targeted Drug Delivery …, 2019 - Elsevier
gene delivery purposes where PEI-interleukin 12 (PEI-IL-12) … grafted with chitosan to make
copolymer (CS-graft-1.8 K PEI) … The targeted HA-PEI/PEG nanoparticles displayed increased …

Chemo-photodynamic combined gene therapy and dual-modal cancer imaging achieved by pH-responsive alginate/chitosan multilayer-modified magnetic …

H Yang, Y Chen, Z Chen, Y Geng, X Xie, X Shen… - Biomaterials …, 2017 - pubs.rsc.org
… Au and superparamagnetic iron oxide (Fe 3 O 4 ) nanomaterials have provided many exciting
… Superparamagnetic iron oxide (Fe 3 O 4 ) nanoparticles are the most commonly used T 2 -…

Chitosan-based nanoparticles for nucleic acid delivery: technological aspects, applications, and future perspectives

M Karayianni, T Sentoukas, A Skandalis, N Pippa… - Pharmaceutics, 2023 - mdpi.com
… to develop safe and efficient gene delivery systems, and chitosanchitosan (dCS) conjugated
with linear PEI was used as the DNA encapsulating core, while dCS conjugated with PEG

Biodegradable polymers for gene delivery

TJ Thomas, HA Tajmir-Riahi, CKS Pillai - Molecules, 2019 - mdpi.com
… This review summarizes mechanistic aspects of gene delivery and the development of … of
PEI with chitosan, PEG and dextran also provided efficient and biodegradable gene delivery