… functions mediated by phosphatidylinositol (4,5)-bisphosphate (PI(4,5)P 2 ; PIP 2 ) involve
clustering … no proteins) it is still possible to consider some of the biological implications of the …

… of the full gamut of PI(4,5)P 2 function has been lacking in … brief but broad summary of
PI(4,5)P 2 function in cell biology. … Clustering of PI(4,5)P 2 can be induced and maintained by …

… Importantly, we also focused on the role of membrane lipid composition in the clustering …
is also observed for low SM content, confirming the biological relevance of this dependence. …

… -regulated protein is inactivated or activated to exert its effect … to explain how PI(4,5)P2 might
function in the complex … of PI(4,5)P2, suggesting that local clustering of PI(4,5)P2 that formed …

… , cell biology and physiology owing to its diverse functions at … phosphorylation by two lipid
kinases, PI 4-kinase (PI4K) and … strongly suggest that PI(4,5)P 2 clusters in the cytoplasmic …

… or affect each other’s impact. The chapters in this volume on “Cholesterol and PI(4,5)P 2 in
Vital Biological Functions: … cholesterol and PI(4,5)P 2 in a variety of biological systems and …

… controls a specific pool of PI(4,5)P 2 which is seen as clusters by anti-PI(4,5)P 2 antibody
labelling [69… Distribution and reported biological functions of lipid kinases that synthesize PI(4,5)…

… We propose that PIP2 cation-bridged cluster formation, which might be similar to … biological
membranes. To our knowledge, this study provides the first evidence of PIP2 forming clusters …

… PI(4,5)P 2 local environment can affect PI(4,5)P 2 headgroup charge, a crucial feature
responsible for a lot of its biological function… PI species can co-cluster with PI(4,5)P 2 , albeit to a …

… to measuring PI(3,4,5)P 3 and PI(3,4)P 2 still rely on radio-… or 32 P-Pi) and a compatible
biological system (usually cells in … recruitment of Lpd, where it clusters and tethers members of …