… required for TCR-induced T cell activation, … (NF-κB) reporter gene in transfected Jurkat
T cells (36). To more rigorously explore the importance of pTyr binding for PKCθ’s TCR-induced …

… (PKC θ) activation, calcium mobilization, and the translocation of the nuclear factor of activated
T-cells (NF-AT) and the nuclear factor κB (NF-κB… that a normal immune system is essential …

… T cell activation, PKC-θ not only still bound to the p65 subunit (also known as RelA) of NF-κB
through Ser536 phosphorylation but also … that nuclear translocation of PKC-θ is required for …

… 1 mediates TCR-induced T cell migration and activation by … of PDK1 in T cells abrogates
activation of NF-κB and PKCθ … , immature/mature T cells, and natural killer cells 165,168,169 …

… Vav and PKCθ is required for TCR-induced T cell activation. … that PKCθ acts downstream
of the NF-κB pathway, leading to IL-2 transcription in SEC2/ST-4–induced T-cell activation. …

… for T lymphocytes through targeting the PKC–NF–κB pathway. … collected from the wing
vein from 21-day-old chicken. Preparations of … To clarify this, further study was necessary. …

… receptors necessary for full T lymphocyte activation. By … of CD28 contribution to TCR-induced
NF-κB activation is the … of TCR recruits and activates IKKα and a non-canonical NF-κB2-like …

… that PKC-θ −/− T cells are unable to respond to TCR stimulation. We report a role of PKC-θ on
DC activation and suggest that the … Although we demonstrate that PKC-θ is required for the …

… Double deficient mice had a severe reduction in mature HSA … TNF induced signalling is not
essential for NF-κB mediated IL… Many immature dendritic cells lie resident within the tissues, …

… required for activation, proliferation, differentiation and survival of immune … activated leads
to the recruitment and activation of NF-κB, AP-1 and NF-AT (nuclear factor of activated T cells) …