Therapeutic effects of paclitaxel loaded polyethylene glycol-polylactic acid-glycolic acid copolymer nanoparticles on pancreatic cancer in rats

Y Fu, L Tan, L Meng, X Lei - … Nanoscience and Nanotechnology, 2020 - ingentaconnect.com
… of paclitaxel PEG-PLGA nanoparticles emulsified in tpgs (PTX-pegpllga-np), for high drug
loading; and to study its effect on … show that PTX-PEGPLGA-NP has a sustained release effect. …

Paclitaxel loaded vitamin E-TPGS nanoparticles for cancer therapy

B Gorain, H Choudhury, M Pandey… - Materials Science and …, 2018 - Elsevier
… Modified single emulsion solvent extraction/evaporation technique – – – PLGA-TPGS NPs
resulted in high entrapment efficiency for PTX along with controlled release profile over a …

Influence of emulsifiers on the formation and in vitro anticancer activity of epirubicin loaded PLGA nanoparticles

O Esim, NK Bakirhan, M Sarper, A Savaser… - Journal of Drug Delivery …, 2020 - Elsevier
… Hence, selection of optimum surfactant is critical to obtain nanoparticles with a desired
effect… min and a controlled release. The initial burst release could be due to the release of drug …

Paclitaxel-loaded star-shaped copolymer nanoparticles for enhanced malignant melanoma chemotherapy against multidrug resistance

Y Su, J Hu, Z Huang, Y Huang, B Peng… - Drug design …, 2017 - Taylor & Francis
… ) nanoparticles (NPs) (shortly PTX-loaded CA-PLGA-TPGS NPs) … used as drug carriers allow
sustained release, have high … anticancer drug PTX and the emulsifier TPGS. In the end, the …

Preparation of Vorapaxar loaded with Vitamin E TPGS and PVA emulsified PLGA nanoparticles In vitro studies

AM Jasim, HF Hasan, MJ Awady - Research Journal of …, 2019 - indianjournals.com
… Our study evaluated the effect of the organic phase with … In fact PLGA-TPGS polymer can
be utilized for nanoparticles as … drug release, cellular uptake and cytotoxicity of paclitaxel

Using PVA and TPGS as combined emulsifier in nanoprecipitation method improves characteristics and anticancer activity of ibuprofen loaded PLGA nanoparticles

A Sahin, F Spiroux, I Guedon, FB Arslan… - Die Pharmazie-An …, 2017 - ingentaconnect.com
… was to evaluate emulsifier effect on … (PLGA TPGS/PVA NPs) as emulsifier. This comparison
showed that the addition of TPGS increased the EE and decreased the PDI and burst release

Combination of Paclitaxel and R-flurbiprofen loaded PLGA nanoparticles suppresses glioblastoma growth on systemic administration

S Caban-Toktas, A Sahin, S Lule, G Esendagli… - International Journal of …, 2020 - Elsevier
effects of NPs or CS coating on the cells. Expectedly, paclitaxel-loaded NPs displayed substantial
cytotoxic effect … and PVA emulsified NPs, respectively) and , ǂ p < 0.05 paclitaxel and R…

Recent advances in TPGS-based nanoparticles of docetaxel for improved chemotherapy

H Choudhury, B Gorain, M Pandey, SA Kumbhar… - International journal of …, 2017 - Elsevier
… agent in the circulation, controlled release in the blood, and … DTX has been found to be more
effective than paclitaxel in … SPIO encapsulation within PLGA-TPGS NPs without affecting its …

Sorafenib-loaded PLGA-TPGS nanosystems enhance hepatocellular carcinoma therapy through reversing P-Glycoprotein-Mediated multidrug resistance

M Tang, Y Huang, X Liang, Y Tao, N He, Z Li, J Guo… - AAPS …, 2022 - Springer
… ) nanoparticles (SPTNs). SPTNs were successfully synthesized through an ultrasonic emulsion
… to an improved intratumoral accumulation of nanoparticles based on EPR effect. With the …

[HTML][HTML] Employing a PLGA-TPGS based nanoparticle to improve the ocular delivery of Acyclovir

M Alkholief, H Albasit, A Alhowyan, S Alshehri… - Saudi Pharmaceutical …, 2019 - Elsevier
… Given all the potential advantages of using TPGS-emulsified … had no effect on the cumulative
amount of ACY released in … that PLGA-TPGS-NPs facilitated sustained release of ACY as …