Cellular mechanisms of aortic aneurysm formation

RA Quintana, WR Taylor - Circulation Research, 2019 - Am Heart Assoc
… thoracic and abdominal aortic aneurysms share … pathophysiology of aortic aneurysms. This
review examines the various proposed cellular mechanisms responsible for aortic aneurysm

Abdominal aortic aneurysm: update on pathogenesis and medical treatments

J Golledge - Nature Reviews Cardiology, 2019 - nature.com
cell-based strategies for this disease. This Review summarizes the latest research findings
and current theories on AAA pathogenesis, … the mechanisms involved in AAA pathogenesis

Mechanisms of abdominal aortic aneurysm progression: A review

JP Gao, W Guo - Vascular Medicine, 2022 - journals.sagepub.com
… the choice of treatment method of AAA. Even so, the … mechanism by which endothelial cells
can transform the mechanical shear force felt on the cell surface into intracellular biochemical

Cellular signaling in abdominal aortic aneurysm

Z Li, W Kong - Cellular signalling, 2020 - Elsevier
… and pathogenesis, there is a lack of overall understanding of the role of cellular signaling
in … involvement of signaling networks in different cellular mechanisms of AAA pathogenesis. …

[HTML][HTML] Aortic aneurysms: current pathogenesis and therapeutic targets

MJ Cho, MR Lee, JG Park - Experimental & Molecular Medicine, 2023 - nature.com
… are unknown pathogenic mechanisms involved in cellular … and current pathogenic
mechanisms of aortic aneurysms, … was increased during abdominal aortic aneurysm progression, …

Pathophysiology of abdominal aortic aneurysm: Biomarkers and novel therapeutic targets

M Torres-Fonseca, M Galan, D Martinez-Lopez… - Clínica e Investigación …, 2019 - Elsevier
… Studying the different cellular and molecular mechanisms which modulate the pathological
vascular remodelling will make it possible to determine with greater accuracy the processes …

[HTML][HTML] The role of epigenetic modifications in abdominal aortic aneurysm pathogenesis

K Mangum, K Gallagher, FM Davis - Biomolecules, 2022 - mdpi.com
aneurysm formation [13]. Epigenetic mechanisms cause dysregulated expression of aneurysm
… has been conducted on the mechanisms of epigenetic regulation of cellular activation in …

[HTML][HTML] Endothelial dysfunction in the pathogenesis of abdominal aortic aneurysm

E DeRoo, A Stranz, H Yang, M Hsieh, C Se, T Zhou - Biomolecules, 2022 - mdpi.com
… and cellular mechanisms underlying AAA pathogenesis remain … Recent studies utilizing
single-cell RNA sequencing … their transcriptional profiles, in aortic aneurysm tissue. This review …

[HTML][HTML] The important role of endothelium and extracellular vesicles in the cellular mechanism of aortic aneurysm formation

K Mikołajczyk, D Spyt, W Zielińska, A Żuryń… - International journal of …, 2021 - mdpi.com
… many factors involved in the pathogenesis of aortic aneurysms that regulate the complexity
… molecular mechanism underlying the dramatically elevated risk of abdominal aortic aneurysm

[HTML][HTML] Immune and inflammatory mechanisms of abdominal aortic aneurysm

AC Marquez-Sanchez, EK Koltsova - Frontiers in immunology, 2022 - frontiersin.org
… and discuss how pathogenic immune cell activation is … mechanisms implicated to the control
of AAA development and briefly highlight local and systemic factors impacting immune cell