How I treat pediatric acute myeloid leukemia

JE Rubnitz, GJL Kaspers - Blood, The Journal of the American …, 2021 - ashpublications.org
… Treatment outcomes for pediatric patients with acute myeloid leukemia (AML) have continued
to lag behind outcomes reported for children with acute lymphoblastic leukemia (ALL), in …

Pediatric acute myeloid leukemia—past, present, and future

D Reinhardt, E Antoniou, K Waack - Journal of clinical medicine, 2022 - mdpi.com
… This review reports about the main steps of development in pediatric acute myeloid
leukemia (AML) concerning diagnostics, treatment, risk groups, and outcomes. Finally, a …

Cytogenetics of pediatric acute myeloid leukemia: a review of the current knowledge

J Quessada, W Cuccuini, P Saultier, M Loosveld… - Genes, 2021 - mdpi.com
Pediatric acute myeloid leukemia is a rare and … current WHO classification of acute myeloid
leukemia, where there … an updated review of cytogenetics in pediatric AML, describing well-…

[HTML][HTML] Current treatment for pediatric acute myeloid leukemia

HJ Im - Blood research, 2018 - synapse.koreamed.org
Pediatric acute myeloid leukemias (AMLs) are a … Recent improvements in the outcomes of
pediatric AML reflect the … the survival rates of patients with pediatric AML. As a result, several …

A new genomic framework to categorize pediatric acute myeloid leukemia

M Umeda, J Ma, T Westover, Y Ni, G Song… - Nature Genetics, 2024 - nature.com
… Recent studies on pediatric acute myeloid leukemia (pAML) have revealed pediatric-specific
driver alterations, many of which are underrepresented in the current classification schemas…

Pediatric relapsed acute myeloid leukemia: a systematic review

AE Hoffman, LJ Schoonmade… - Expert review of …, 2021 - Taylor & Francis
Introduction: Pediatric relapsed acute myeloid leukemia (AML) remains lethal in the majority
of cases, despite intensive therapy. Randomized trials are largely lacking, and the main …

Successes and challenges in the treatment of pediatric acute myeloid leukemia: a retrospective analysis of the AML-BFM trials from 1987 to 2012

M Rasche, M Zimmermann, L Borschel, JP Bourquin… - Leukemia, 2018 - nature.com
… (OS) of pediatric patients with acute myeloid leukemia (AML) … and clinical data of 1940
pediatric AML patients (younger than … contributed to better outcome in pediatric AML, our analysis …

The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions

H Bolouri, JE Farrar, T Triche Jr, RE Ries, EL Lim… - Nature medicine, 2018 - nature.com
… of pediatric acute myeloid leukemia (… all pediatric cases. New mutations in GATA2, FLT3
and CBL and recurrent mutations in MYC-ITD, NRAS, KRAS and WT1 were frequent in pediatric

Clinical challenges in de novo pediatric acute myeloid leukemia

K Klein, V de Haas, GJL Kaspers - Expert Review of Anticancer …, 2018 - Taylor & Francis
… Cytogenetically and molecularly defined prognostic groups in pediatric acute myeloid
leukemia. … Pitfalls and clinical decision making in pediatric acute myeloid leukemia. …

Genetic mechanisms of primary chemotherapy resistance in pediatric acute myeloid leukemia

NA McNeer, J Philip, H Geiger, RE Ries, VP Lavallee… - Leukemia, 2019 - nature.com
Acute myeloid leukemias (AML) are characterized by mutations of tumor suppressor and
oncogenes, involving distinct genes in adults and children. While certain mutations have been …