[HTML][HTML] Study on analysis of peripheral biomarkers for Alzheimer's disease diagnosis

P Rani, S Krishnan, C Rani Cathrine - Frontiers in neurology, 2017 - frontiersin.org
… The main objective of the present study is to evaluate the peripheral levels of redox markers,
oxidized glutathione (GSSG) is based on the glutathione recycling system using glutathione

Potential oxidative stress biomarkers of mild cognitive impairment due to Alzheimer disease

A García-Blanco, M Baquero, M Vento, E Gil… - Journal of the …, 2017 - Elsevier
… However, oxidative stress peripheral levels might be … associated with damage to proteins
(protein oxidation products, enzyme … that the glutathione reductase/glutathione peroxidase ratio …

Oxidative stress, protein modification and Alzheimer disease

A Tramutola, C Lanzillotta, M Perluigi… - Brain research bulletin, 2017 - Elsevier
… such as superoxide dismutase (SOD), glutathione peroxidase (GPx), … common markers of
protein modifications, protein oxidation/… that lead from normal aging to development of AD. …

Protein Oxidation in Aging and Alzheimer's Disease Brain

R Sultana, DA Butterfield - Antioxidants, 2024 - mdpi.com
… GSH level is maintained by the enzyme glutathione reductase … developed for the detection
of oxidatively modified proteins. … of markers of oxidative and nitrosative stress, ie, protein

Markers of oxidative damage to lipids, nucleic acids and proteins and antioxidant enzymes activities in Alzheimer's disease brain: a meta-analysis in human …

M Zabel, A Nackenoff, WM Kirsch, FE Harrison… - Free Radical Biology …, 2018 - Elsevier
… change in level for markers of lipid and protein oxidation. We … to be no difference in glutathione
levels across multiple brain … which lowered peripheral levels of oxidative stress improved …

[HTML][HTML] Oxidative stress, amyloid-β peptide, and altered key molecular pathways in the pathogenesis and progression of Alzheimer's disease

DA Butterfield, D Boyd-Kimball - Journal of Alzheimer's …, 2018 - content.iospress.com
… are measures of protein oxidation (protein carbonyls; 3-… of reduction of oxidized glutathione
via glutathione reductase, which is … Similarly, we investigated mitochondria from peripheral

Glutathione: an old and small molecule with great functions and new applications in the brain and in Alzheimer's disease

M Haddad, V Hervé, MR Ben Khedher… - Antioxidants & Redox …, 2021 - liebertpub.com
… were developed to restore its intracellular level with the l-… that the levels of GSH and other
oxidative markers were lower in … The extent of oxidation in peripheral blood is greater than the …

[HTML][HTML] Altered central and blood glutathione in Alzheimer's disease and mild cognitive impairment: A meta-analysis

JJ Chen, M Thiyagarajah, J Song, C Chen… - Alzheimer's Research & …, 2022 - Springer
… Increasing evidence implicates oxidative stress (OS) in AlzheimerDevelopment of interventions
targeting amyloid beta plaques … Nonetheless, our peripheral GSH findings suggests that …

Sialic acid associated with oxidative stress and total antioxidant capacity (TAC) expression level as a predictive indicator in moderate to severe Alzheimer's disease

J Yadav, AK Verma, RK Garg, K Ahmad… - Experimental …, 2020 - Elsevier
peripheral blood samples in moderate to severe Alzheimer'sprotein oxidation amount based
on the reaction of DNPH with … levels of Catalase, Superoxide dismutase, Glutathione, and …

[HTML][HTML] Oxidant/antioxidant imbalance in Alzheimer's disease: therapeutic and diagnostic prospects

J Wojsiat, KM Zoltowska… - Oxidative medicine …, 2018 - hindawi.com
… damage present in the brain is reflected in peripheral cells, … by glutathione peroxidase (GPx)
to form glutathione disulfide (… al., “Excess brain protein oxidation and enzyme dysfunction in …