Diagnosis of adverse local tissue reactions following metal-on-metal hip arthroplasty

BP Chalmers, KI Perry, MJ Taunton, TM Mabry… - Current reviews in …, 2016 - Springer
serum metal ion levels [22]. Several studies have shown … Deep periprosthetic joint
infection (PJI) should always be … that MRI better predicts the severity and degree of soft tissue

What surgeons need to know about adverse local tissue reaction in total hip arthroplasty

DJ Hall, R Pourzal, JJ Jacobs - The Journal of arthroplasty, 2020 - Elsevier
… and periprosthetic tissues due to large amounts of metal debris. However, it should be mentioned
that the cellular response to this type of … It is important to note that the serum metal level

Metal-on-metal hip joint prostheses: a retrospective case series investigating the association of systemic toxicity with serum cobalt and chromium concentrations

JH Ho, JB Leikin, PI Dargan, JRH Archer… - Journal of Medical …, 2017 - Springer
… the two with an acceptable prediction error, from which … are consistent with published data
for adverse local tissue reactions, which shows that whilst reported metal ion concentrations

Blood metal levels, leucocyte profiles, and cytokine profiles in patients with a modular dual-mobility hip prosthesis: early results from a prospective cohort study

DC Markel, T Bou-Akl, MD Rossi… - The Bone & Joint …, 2019 - boneandjoint.org.uk
… , we found no issues of concern from metal ion levels or serum … As metal ion analysis alone
cannot be used to predict the … the early detection of periprosthetic pathological changes, such …

[HTML][HTML] Molecular pathology of adverse local tissue reaction caused by metal-on-metal implants defined by RNA-seq

CG Salib, EA Lewallen, CR Paradise, ME Tibbo… - Genomics, 2019 - Elsevier
… with sequential assessments of serum metal ion levels [42,57]. … therein will help predict which
patients are at an increased … release metal ions into the joint space, causing periprosthetic

Metal concentrations in the blood and tissues after implantation of titanium growth guidance sliding instrumentation

E Lukina, A Laka, M Kollerov, M Sampiev, P Mason… - The Spine Journal, 2016 - Elsevier
not yet been investigated. The aim of our study was to measure the content of metal ions in
the blood and tissues that … with spinal instrumentation might not be used in predicting clinical …

Metals measurements in body tissues and fluids: Toxicological and clinical importance of standardizing quality analytical methods for differentiating cobalt partitioning …

B Kerger, R Gerads, H Gurleyuk… - … on Beyond the …, 2018 - asmedigitalcollection.asme.org
… (Co) concentrations in periprosthetic tissues and body fluids … in assessing whether or not
metal-induced cytotoxicity played a … in human serum [11] but, to our knowledge, has not been …

Adverse reactions to metal on polyethylene implants: Highly destructive lesions related to elevated concentration of cobalt and chromium in synovial fluid

F Eltit, A Assiri, D Garbuz, C Duncan… - … Research Part A, 2017 - Wiley Online Library
… , there are no alerts regarding metal or serum ion levels in … of necrosis and destruction
of the periprosthetic soft-tissues. … of metals in patients' blood is a useful tool to predict the …

The Use of Semiquantitative Histology for Reporting Periprosthetic Tissue Features: A Review

P Campbell, M Nguyen, N Yuan - … on Beyond the …, 2018 - asmedigitalcollection.asme.org
… ] reported that tissue metal levels, but not serum metal levels, predicted the degree of tissue
… features in the tissue of patients with pseudotumors at a cut-off level ALVAL score of five or …

[PDF][PDF] Metal-on-Metal Hip Replacement: MRI Signal Intensities of Different Body Tissues and Their Relations to Blood Metal Ion Levels

MD Einat Slonimsky, MD Assaf Kadar… - ima.org.il
… suggest that metal deposition occurs in the periprosthetic … to quantitatively predict the expected
SI of various tissues … inversely correlated with serum glutamate concentration. Consistently…