… tacrolimus dose 6 months preconversion and postconversion were examined. CYP3A5 was
genotyped … way to optimize personalized immunosuppressive therapy of tacrolimus before …

… CYP3A5 genotype plays a role in determining the impact of … The contribution of CYP3A5
genotype to tacrolimus dosing … effect of renal CYP3A5 genotype on risk of tacrolimus-induced …

… predict the appropriate dosage required for a given patient. … a CYP3A5 genotype-based TAC
starting dose, with CYP3A5 … authors that renal induction of CYP3A5 and ABCB1 expression …

… risk of tacrolimus-induced nephrotoxicity … personalized dosing strategy improves clinical
outcomes [Citation11]. Therefore, routine use of CYP3A5 genotype to guide tacrolimus dosing …

… on CYP3A5 and PPARA were identified as determining and … and PPARA pre-transplant
genotyping may help to obtain … and therefore helping to maintain suppression of alloimmunity …

… doses of TAC in patients who express CYP3A5 or performing genotyping prior to transplant
in order to determine the … of adaptation of initial tacrolimus dosing to cyp3a5 genotype. Am J …

… of antithymocyte globulin at first day post-transplantation or basiliximab induction on days 0
… Thus, CYP3A5 genotyping can be helpful in guiding initial TAC dosing in order to achieve …

… dose was defined as the sum of the morning dose, given … , inappropriate dosing of tacrolimus
can also induce kidney injury… tacrolimus metabolism was the recipient's CYP3A5 genotype, …

… been developed to improve personalized tacrolimus treatment. … for dosing tacrolimus, based
on the CYP3A5 genotype [1] … Moreover, although tacrolimus-induced nephrotoxicity is likely …

… (ATG) or basiliximab as induction therapy, followed by Tac … of the alleles CYP3A4*22 and
CYP3A5*1 in the Caucasian … each metaboliser group established according to genotype, we …