… midazolam in preterm infants. This model indicated a very low first-pass effect by intestinal
and hepatic metabolism by CYP3A in preterm infants … intravenous acetaminophen in neonates…

… Three, do not use morphine infusion in preterm infants under … , such as midazolam (bolus
0.05–0.2 mg/kg intravenously over … pharmacokinetics and pharmacodynamics of sedative and …

… studies investigating circadian rhythm effects on midazolam in children [Citation135] …
pharmacology of drugs used in children. The inability to measure the concentration of intravenous …

… and cimetidine or ranitidine had no clinically significant effect on the pharmacokinetics and
pharmacodynamics of midazolam. These data indicate that intravenous midazolam can be …

… Because of hypotensive effects in preterm neonates, sedation with midazolam should …
intravenous access, intranasal midazolam allows for provision of sedation. Intranasal midazolam …

A Dissertation on “ A comparative study of oral midazolam and oral melatonin for premedication
in Paediatric Anaesthesia ” S Page 1 A Dissertation on “ A comparative study of oral …

… Absorption In the early phase of their critical care, the intravenous route ensures full drug …
for the objective and continuous evaluation of respiration and drug effects in preterm infants. …

… optimal dose of clonidine and midazolam in the PICU (CloSed … an IV dose of 2 µg/kg for
procedural pain in preterm infants. … fentanyl, clonidine and midazolam were defined in specific …

… In preterm infants, the clearance was reported to be lower (… in preterm infants than in an
infant of 4 kg. A study with critically ill children reported a clearance of 1.11 L h −1 for an infant of …

… in stomach pH are generally not seen in preterm infants who have little free acid during the
… , intranasal midazolam had an onset of action as fast as intravenous midazolam but was …