[HTML][HTML] Sedation and analgesia from prolonged pain and stress during mechanical ventilation in preterm infants: is dexmedetomidine an alternative to current practice …

S Ojha, J Abramson, J Dorling - BMJ Paediatrics Open, 2022 - ncbi.nlm.nih.gov
… on pharmacokinetics–pharmacodynamics in preterm infants are … of very preterm infants who
receive intravenous morphine … in use of midazolam with fewer infants receiving midazolam, …

Treating disorders of the neonatal central nervous system: pharmacokinetic and pharmacodynamic considerations with a focus on antiepileptics

MD Donovan, GB Boylan, DM Murray… - … Pharmacology, 2016 - Wiley Online Library
… of centrally acting drugs in both term and preterm neonates is … A agonists phenobarbital
and midazolam, and dramatic … Both oral and intravenous formulations found to have equal (…

[HTML][HTML] Search for the ideal route of premedication in children.. far from over?

S Sengupta, P Bhattacharya, DS Nag… - Indian Journal of …, 2022 - journals.lww.com
… , pharmacokinetics, and pharmacodynamics of the administered … /kg with regard to intravenous
acceptance before induction of … Oral midazolam is the most commonly used paediatric …

[HTML][HTML] A physiology-based pharmacokinetic framework to support drug development and dose precision during therapeutic hypothermia in neonates

A Smits, P Annaert, S Van Cruchten… - … in Pharmacology, 2020 - frontiersin.org
… to 7) in term and late preterm neonates with moderate-to-severe HIE, … iv midazolam,
several sensitivity analyses were conducted to evaluate the possible impact of TH on midazolam

Prevention and management of procedural pain in the neonate: an update

E Keels, N Sethna, KL Watterberg, JJ Cummings… - …, 2016 - publications.aap.org
… of pain in neonates, particularly preterm infants, is important not … evidence to recommend
midazolam infusions for sedation in … Studies on pharmacokinetics and pharmacodynamics of …

Managing procedural pain in the neonate using an opioid-sparing approach

A Squillaro, EM Mahdi, N Tran, A Lakshmanan… - Clinical …, 2019 - Elsevier
… pain management in term and preterm neonates and infants. … than infants randomly assigned
to midazolam or saline … the neonate's unique physiology, as their pharmacodynamics and …

Pharmacodynamics and pharmacokinetics of morphine after cardiac surgery in children with and without Down syndrome

AJ Valkenburg, EAM Calvier, M van Dijk… - Pediatric Critical Care …, 2016 - journals.lww.com
… Anesthesia was induced with IV midazolam (optional; 100–… of anesthesia instead of midazolam
and ketamine. Pancuronium (… Morphine glucuronidation in preterm neonates, infants and …

Meeting Challenges of Pediatric Drug Delivery: The Potential of Orally Fast Disintegrating Tablets for Infants and Children

K Golhen, M Buettcher, J Kost, J Huwyler, M Pfister - Pharmaceutics, 2023 - mdpi.com
… cost-effective than conventional oral midazolam syrup and has a … Developmental pharmacology
concerns related to excipients … Preterm neonates may be at increased risk of propylene …

[PDF][PDF] Clinical Pharmacology of Ceftazidime in Neonates: Effects and Pharmacokinetics

GM Pacifici, G Marchini - International Journal of Pediatrics, 2017 - sid.ir
… ceftazidime pharmacokinetics in preterm infants and related … dosage recommendations for
preterm infants on day 3 of life. … kg intravenous dose) were evaluated in 136 preterm infants on …

[PDF][PDF] Safety comparison between different anesthesia protocols regarding premature infants undergoing laser therapy for Retinopathy of Prematurity-Systematic …

A Gavriilidou - … of Scientific Publications: Aristotle University of …, 2022 - ikee.lib.auth.gr
… pentazocine and midazolam; and fentanyl and midazolam, compared … that affects the retina
of preterm infants and it was first … , with a typical pharmacodynamic profile of opioid analgesic …