… in plasma or other tissues or biological matrices. Total drug exposure … interactions, microbiota,
or disease(s) status. We anticipate that pharmacometabolomics and pharmacogenomics …

… , transfer between body compartments, biological transformation, and elimination. Many
physiological variations between men and women may account for pharmacokinetic variances, …

… , and environmental factors mutually interact in defining sex/gender differences, and at the
… may strongly differ between males and females. While sex refers to biological and genetic …

… a product of the gene environment interaction is also vital to our … Both the pharmacokinetic
and pharmacodynamic components of … Pharmacogenetics of tamoxifen bio transformation is …

… Genomic differences between individuals are present approximately every 300–1000 …
–drug interactions, which may be attributed to the altered pharmacokinetic or pharmacodynamic …

… With the emergence and development of pharmacogenomics, it is possible to discover …
variations in drug metabolizing enzymes, drug transporters, and direct and indirect interactions …

… as a biological variable in drug delivery, pharmacokinetic … attention to differences between
women and men in terms of … that differences in communication tactics between males and …

… adverse drug reactions differ between men and women. The … to these pharmacodynamic
interactions. In one example, … of women is needed in order to utilized a pharmacogenomic …

… Heterogeneity in study design and biological interactions … biological mechanisms which may
be contributing to the sex … of 50% difference between males and females for at least one PK …

… , men showed no difference and women showed only a relatively small difference between
… to UGT1A3-mediated drug-drug interactions. Interestingly, nisoldipine has increased the …