Involvement of NMDA-AKT-mTOR signaling in rapid antidepressant-like activity of chaihu-jia-longgu-muli-tang on olfactory bulbectomized mice

X Wang, Z Zou, Q Shen, Z Huang, J Chen… - … in Pharmacology, 2019 - frontiersin.org
… We aimed to test a traditional Chinese herbal medicine CLM for a rapid antidepressant
activity and to examine associated neuromolecular substrate. We found a single dose of CLM …

Catalpol exerts antidepressant-like effects by enhancing anti-oxidation and neurotrophy and inhibiting neuroinflammation via activation of HO-1

X Wu, C Liu, J Wang, Y Guan, L Song, R Chen… - Neurochemical …, 2022 - Springer
… In recent years, the development of new antidepressants from natural herbal medicine has
… In recent years, the utilization of target antagonists to diagnose molecular targets of drug

Antidepressant-Like Effect of Salvadora persica Extract in Rat Model of Depression

RMM Almarashi - 2017 - platform.almanhal.com
… Salvadora persica (SP) has been used as a medicinal purpose among global Muslim
community. The present work was designed to study the antidepressant-like effect of SP extract in …

The development of novel antidepressants: Focus on plant-based drugs

AT El-Alfy - … for Antidepressants-An Integrative View of Drug …, 2017 - books.google.com
… to drug development. The current chapter provides an overview of currently available herbal
products that have preclinical and clinical evidence … significant antidepressant-like effects in …

[HTML][HTML] Antidepressant-like effect of active fraction of polyrhachisvicina roger in a rat depression model

W Guining, C Shifeng, S Qibiao, S Hua, L Meiyu… - Journal of Traditional …, 2018 - Elsevier
… Experiment design and drug treatment … board under anesthesia by diethyl ether, and the
prefrontal cortex and hippocampus were dissected on ice for later neurochemical assessment. …

Piper sarmentosum Roxb. produces antidepressant-like effects in rodents, associated with activation of the CREB-BDNF-ERK signaling pathway and reversal of HPA …

Q Li, FL Qu, Y Gao, YP Jiang, K Rahman… - Journal of …, 2017 - Elsevier
antidepressant-like effects, Piper sarmentosum (PS) is one of them. PS is a Chinese herbal
… by a one-way ANOVA with drug treatment as the factor and revealed a significant effect of …

Advances in the preclinical study of some flavonoids as potential antidepressant agents

LJ German-Ponciano, GU Rosas-Sánchez… - …, 2018 - Wiley Online Library
… and neurochemical effects and the apparent mechanism of action of their preclinical
antidepressant-like effects. … Hesperidin is a flavonoid that has different pharmacological actions …

[PDF][PDF] Herbal Medicines and Phytochemicals for Obsessive Compulsive Disorder (OCD)

Z Ayati, J Sarris, D Chang - minerva-access.unimelb.edu.au
evidence. Thereby the present paper aims to review potential anti-OCD herbal and …
evidence for the use of medicinal plants and phytochemicals for the treatment of OCD, …

Neurogenesis-dependent antidepressant-like activity of Hericium erinaceus in an animal model of depression

PS Chong, CH Poon, J Roy, KC Tsui, SY Lew… - Chinese Medicine, 2021 - Springer
… Hericium erinaceus (HE) is a medicinal mushroom that has … evidence has shown that HE
can promote positive nerve and brain health. HE has been shown to possess pharmacological

Medicinal Herbs against Central Nervous System Disorders

A Olatunde, N Munir, G Anywar, M Hanif… - … Therapeutic Effects, 2023 - Wiley Online Library
… officinalis exerted an antidepressant- like effect in mice via … standard drug for depression;
1 mg/kg PO), and bupropion (10 mg/kg PO). They concluded that the antidepressant- like effect