… Abstract: Cancer is a frightful disease that still poses a 'nightmare' worldwide, … treatment
strategy. Plants are repositories for new chemical entities and have a promising cancer research …

… a phase II study to evaluate the combination of pazopanib with weekly paclitaxel in … patients,
4 had stable disease and 2 were not evaluable for response. The pharmacokinetic studies …

… The response to treatment in this study was independent of nectin-4 and PD-L1 expression
… and ICI therapy to either SG or physician’s choice of paclitaxel, docetaxel, or vinflunine. The …

… Nephrotoxicity complicated by hepatic failure and death was … compound of this family,
vinflunine. The only reported adverse … and pharmacokinetic study of oral topotecan, in patients …

… An upcoming phase III trial will compare erdafitinib to either vinflunine, docetaxel, or
pembrolizumab with urothelial carcinoma, based on FGFR alterations and PD-L1 status. The patient …

… medicine for the treatment of various diseases such as hepatic disorders. Phytoestrogens in
… Alkaloids such as vincristine, vindoline, vinblastin, vinflunine, and catharantin in the aerial …

… the occurrence of electrolyte disorders, which can be hazardous and in many cases fatal. The
review … Vinflunine, a new microtubule inhibitor used in small cell lung cancer, also induces …

… Twenty-nine patients were treated with GTI-2040 and docetaxel by iv infusion. Twelve of …
patients in phase II study had stable disease as their response. Two patients developed grade 4/…

… is currently undergoing phase II clinical trial for cancer therapy. Moreover, vinflunine and …
The pharmacokinetic studies displayed a 1.87-fold increment in bioavailability of Nos upon …

… The patient was treated with palliative whole-brain radiotherapy (20 Gy in 5 fractions) and
vinflunine up to 2 cycles between June 2022 and August 2022. Treatment was discontinued …