Combining antivascular endothelial growth factor and anti-epidermal growth factor receptor antibodies: randomized phase II study of irinotecan and cetuximab with …

…, J Lacy, HJ Lenz, U Verma, AB Benson - JNCI: Journal of the …, 2024 - academic.oup.com
epidermal growth factor receptor and antiVEGF drugs. In this randomized multicenter phase
2 study … of ramucirumab to irinotecan and cetuximab improved PFS and disease control rate, …

Combining antivascular endothelial growth factor and anti-epidermal growth factor receptor antibodies: randomized phase II study of irinotecan and cetuximab with …

…, J Lacy, HJ Lenz, U Verma, AB Benson - JNCI: Journal of the …, 2024 - academic.oup.com
… -epidermal growth factor receptor and anti-VEGF drugs. In this randomized multicenter phase
2 study … of ramucirumab to irinotecan and cetuximab improved PFS and disease control rate…

Randomized phase II trial of cixutumumab alone or with cetuximab for refractory recurrent/metastatic head and neck squamous cell carcinoma

R Ferrarotto, WN William Jr, JE Tseng, S Marur… - Oral Oncology, 2018 - Elsevier
Cetuximab, a human-murine monoclonal antibody targeting the epidermal growth factor
receptor (EGFR), is the only … Phase II multicenter study of the antiepidermal growth factor

… phase 2 study of temsirolimus and cetuximab versus temsirolimus alone in recurrent/metastatic, cetuximab‐resistant head and neck cancer: The MAESTRO study

TY Seiwert, S Kochanny, K Wood, FP Worden… - Cancer, 2020 - Wiley Online Library
… This study hypothesized that dual blockade of mammalian target of rapamycin and epidermal
growth factor receptor (… In this multicenter, randomized clinical study, patients with recurrent/…

A randomized controlled trial of epidermal growth factor ointment for treating epidermal growth factor receptor inhibitor‐induced skin toxicities

YS Kim, JH Ji, SY Oh, S Lee, SJ Huh, JH Lee… - The …, 2020 - academic.oup.com
… anti‐EGFR monoclonal antibodies such as cetuximab and … Our previous phase II study has
shown encouraging results … ‐controlled, multicenter, pilot phase III study was performed at 11 …

… blockade with cetuximab and erlotinib combined with anti-VEGF antibody bevacizumab in advanced solid tumors: a phase 1 dose escalation triplet combination trial

V Subbiah, EI Dumbrava, Y Jiang, KZ Thein… - … hematology & oncology, 2020 - Springer
… A triplet combination of epidermal growth factor receptor (EGFR) monoclonal antibody and
… The dose-escalation portion of the study determined the recommended phase II dose (RP2D…

[HTML][HTML] A randomized phase II study comparing the efficacy and safety of the glyco-optimized anti-EGFR antibody tomuzotuximab against cetuximab in patients with …

K Klinghammer, J Fayette, A Kawecki, A Dietz… - ESMO open, 2021 - Elsevier
… the addition of the epidermal growth factor receptor (EGFR) antibody cetuximab to a cisplatin
… The RESGEX study was a phase II, randomized, controlled, open-label, multicenter study of …

Randomized phase II trial of ficlatuzumab with or without cetuximab in pan-refractory, recurrent/metastatic head and neck cancer

JE Bauman, NF Saba, D Roe, JR Bauman… - Journal of Clinical …, 2023 - ascopubs.org
receptor tyrosine kinases (RTKs) that converge on the same downstream pathways, including
other human epidermal growth factor receptor … This multicenter study was conducted at the …

[HTML][HTML] Epidermal growth factor receptor (EGFR) pathway polymorphisms as predictive markers of cetuximab toxicity in locally advanced head and neck squamous …

J Fernández-Mateos, R Seijas-Tamayo, R Mesía… - Oral oncology, 2016 - Elsevier
cetuximab-related toxicity in this study for the first time, they should be interpreted carefully.
The statistical power of this studyPhase II multicenter study of the antiepidermal growth factor

Randomized phase II study of duligotuzumab (MEHD7945A) vs. cetuximab in squamous cell carcinoma of the head and neck (MEHGAN Study)

J Fayette, L Wirth, C Oprean, A Udrea, A Jimeno… - Frontiers in …, 2016 - frontiersin.org
… : This multicenter, open-label, randomized phase II study (… Factors thought to contribute to
cetuximab resistance in … for EGFR and human epidermal growth factor receptor 3 (HER3) (7, 8), …