Lipid–polymer hybrid nanoparticles as a next-generation drug delivery platform: state of the art, emerging technologies, and perspectives

A Mukherjee, AK Waters, P Kalyan… - International journal …, 2019 - Taylor & Francis
… /o/w) is applied for water-soluble drugs ( Figure 4B ). First, the aqueous solution of the drug is
… in an organic solvent (oil phase) containing polymer and lipid to form aw/o mixture. A w/o/w …

Lipid-polymer hybrid nanocarriers for delivering cancer therapeutics

T Date, V Nimbalkar, J Kamat, A Mittal… - Journal of controlled …, 2018 - Elsevier
… for long circulation of siRNA wherein the aqueous solution of siRNA and acetone with G0-…
“differentially charged hollow core/shell lipid-polymer-lipid hybrid nanoparticles” comprised of …

Emergence of polymer-lipid hybrid systems in healthcare scenario

A Jain, L Gautam, N Vishwakarma… - … , and Applications of …, 2021 - igi-global.com
solution, it is heated up to 60-70C. Polymer solution is then added dropwise to the
aqueous solution … The system is referred as Differentially charged hollow core/shell lipidpolymer-lipid

Lipid–polymer hybrid nanocarrier-mediated cancer therapeutics: current status and future directions

NK Garg, N Tandel, RS Jadon, RK Tyagi, OP Katare - Drug discovery today, 2018 - Elsevier
phase (aqueous medium of the lipid vesicles and polymer NPs); and (iv) lipid vesicle-to-polymeric
NP ratio, as reported elsewhere [97]. Anionic polystyrene NPs are used as the core …

Modulation of phase separation at the micron scale and nanoscale in giant polymer/lipid hybrid unilamellar vesicles (GHUVs)

TPT Dao, F Fernandes, E Ibarboure, K Ferji, M Prieto… - Soft Matter, 2017 - pubs.rsc.org
… , important factors such as line tension at lipid polymer/lipid boundaries can be finely modulated
by the … We had exactly the same phase behaviour described above for DOW, 1.5K or 3K …

Lipid–polymer hybrid nanosystems: a rational fusion for advanced therapeutic delivery

S Jain, M Kumar, P Kumar, J Verma… - Journal of Functional …, 2023 - mdpi.com
… In the single-step method, the drug and polymer solution in a water-miscible organic
solvent is added to an aqueous medium encompassing lipids or lipid–PEG, with spontaneous …

Lipid-polymer hybrid nanoparticles: Synthesis strategies and biomedical applications

V Dave, K Tak, A Sohgaura, A Gupta, V Sadhu… - Journal of …, 2019 - Elsevier
… After this, nanoparticle were removed from the mold and with the help of aqueous solution
of lipids nanoparticles were separated from PVA coated PET sheets leading to the formation …

Lipid polymer hybrid carrier systems for cancer targeting: A review

Z Chaudhary, N Ahmed, A . ur. Rehman… - International journal of …, 2018 - Taylor & Francis
… If the drug is soluble in oil phase (water-immiscible organic solvent), then single-phase
emulsion is implied [110]. Double/multiple-emulsion method is used when the substance to be …

Polymer–lipid hybrid nanostructures for drug delivery

LA Gusmão, AC Tedesco - Hybrid Nanomaterials for Drug Delivery, 2022 - Elsevier
solution is created when the lipid from the aqueous medium dissolves and is added to the
solution. The … The core–shell lipid-polymerlipid systems (CSLPL) system consists of a hollow …

[HTML][HTML] Elucidating the nanostructure of small interfering RNA-loaded lipidoid-polymer hybrid nanoparticles

A Aljabbari, AG Lokras, JJK Kirkensgaard… - Journal of Colloid and …, 2023 - Elsevier
… shift in the phase transition temperature of lipidoid, and the thermotropic phase behavior of
… likely to adopt a lamellar phase upon dispersion in aqueous medium, which is in accordance …