Photodynamic inactivation mediated by methylene blue or chlorin e6 against Streptococcus mutans biofilm
M Nie, DM Deng, Y Wu, KT de Oliveira… - Photodiagnosis and …, 2020 - Elsevier
Background An appropriate photosensitizer (PS) for photodynamic inactivation should have
a pronounced antimicrobial efficacy but low dark toxicity. The aim of this study is to
investigate the concentration-dependent antimicrobial efficacies of methylene blue (MB) and
chlorin e6 (Ce6), against Streptococcus mutans biofilms and to compare the efficacies of
these two PSs. Methods The 48-h S. mutans UA159 biofilms, grown on glass coverslips,
were subjected to MB or Ce6 at 25, 50, 100 and 200 μM with or without irradiation by 660 …
a pronounced antimicrobial efficacy but low dark toxicity. The aim of this study is to
investigate the concentration-dependent antimicrobial efficacies of methylene blue (MB) and
chlorin e6 (Ce6), against Streptococcus mutans biofilms and to compare the efficacies of
these two PSs. Methods The 48-h S. mutans UA159 biofilms, grown on glass coverslips,
were subjected to MB or Ce6 at 25, 50, 100 and 200 μM with or without irradiation by 660 …
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