… As shown in Supplemental Table 10, the integration of our results from WES to the SNP
array analysis revealed copy number gains on chromosome 4p (position: 48283-49553810) …

… as a routine analysis. Transcriptome profiling of pituitary neuroendocrine tumors with GH …
that also exhibited increased proliferative activity [59]; this finding suggests a possible utility …

… our findings, we analyzed an independent cohort of 87 pituitary … genomic analysis to date
of a diverse cohort of 178 pituitary adenomas, including 42 adenomas profiled by whole-exome …

… [11] in this study group, but exome analysis of larger group of 42 PitNETs … results provide
a more comprehensive approach to identify the genetic composition of PitNET. Exome analysis …

… Pituitary neuroendocrine tumors (PitNETs, also named pituitary adenomas) are the second
most … One notable finding of this study is that gonadotroph tumors predominantly exhibited …

… The purpose of this study was to analyze the impact of copy … altered genome, varying from
0 to almost 100% of the whole genome. … Our results underline that the quantity of alterations is …

… The high frequency of GNAS mutations in GH-PAs is consistent with previous findings 4 …
tumors with a mutation in a potentially actionable gene in one of these 7 pathways. This analysis …

… Recent analysis of pituitary adenomas using whole-exome … results of whole exome sequencing
of 42 pituitary adenomas (… and 11 as the most common genomic alteration and found that …

… Pituitary adenomas were diagnosed on the basis of radiological findings and hormonal
screening. … Copy number analysis revealed a heterozygous germline deletion of a segment on …

… Here, we combined various -omics analyses on a series of 134 PitNETs of high quality and
purity, carefully collected from a single expert center. We included all histological, secretory, …