Plants of the genus Vitis: Phenolic compounds, anticancer properties and clinical relevance

B Salehi, S Vlaisavljevic, CO Adetunji… - Trends in Food Science …, 2019 - Elsevier
Trends in Food Science & Technology, 2019Elsevier
Background Vitis genus comprised about 70 species. Concerning its pharmacological
properties, V. vinifera is the most studied one, but there are other species with interest.
Scope and approach Therefore, this review aims to provide an updated overview on
bioactive phytochemicals present in food products (grapes and wine) of V. vinifera and other
Vitis species, as well as in different underused bioresources (stem, leaves, seeds, wine
pomace, etc.). Moreover, due to their promising perspectives in the field of anticancer drug …
Background
Vitis genus comprised about 70 species. Concerning its pharmacological properties, V. vinifera is the most studied one, but there are other species with interest.
Scope and approach
Therefore, this review aims to provide an updated overview on bioactive phytochemicals present in food products (grapes and wine) of V. vinifera and other Vitis species, as well as in different underused bioresources (stem, leaves, seeds, wine pomace, etc.). Moreover, due to their promising perspectives in the field of anticancer drug discovery, this bioactivity has been covered as well as the contribution that Vitis phenolic compounds has.
Findings and conclusions
Among the plant products reviewed, grape seed extracts was the most investigated at preclinical phase, hence exhibiting a promising potential as anticancer drugs. However, an evidence-based clinical efficacy is still lacking.
Elsevier
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