12 Sacred fortresses

P Burleigh - Architecture and the Body, Science and Culture, 2017 - books.google.com
… built shelters like bunkers, pill boxes and observation towers which … , the crypt encapsulated
both the church’s function as a … For a detailed analysis of the role of vision in Greek culture, …

Colorectal cancer: causes and evidence of chemopreventive treatments

E Pérez-Escalante, R Cariño-Cortés… - Current …, 2018 - ingentaconnect.com
… represent a complex and evolving field of research. … , caused by overexpression in the Polo
kinase (Plk) that regulates … tiator in the formation of aberrant crypts and adenomas due to the …

[PDF][PDF] 5-fluorouracil: Mechanisms of Action (or Resistance) in P53-proficient and-deficient Colorectal Cancer

F Falcone, DB Longley - 2019 - pure.qub.ac.uk
… Using a panel of p53 isogenic models of colorectal cancer, we conducted extensive
phenotypic and functional genomic analyses of the effects of 5-FU and its combination with …

EMT transcription factors in cancer development re-evaluated: Beyond EMT and MET

S Goossens, N Vandamme, P Van Vlierberghe… - … Acta (BBA)-Reviews on …, 2017 - Elsevier
… the apoptotic loss of the crypt base columnar stem cells and … Although we have a good
idea on the spectrum of direct EMT… and how their eventually evolve into a resistant incurable …

Urban geology for the enhancement of the hypogean geosites: The Perugia underground (Central Italy)

L Melelli, F Silvani, M Ercoli, C Pauselli, G Tosi… - Geoheritage, 2021 - Springer
… The iconic image of geology as a science brings to mind natural environments where the …
initial geomorphological arrangement and the successive evolution of the areas coupled with …

Development of MPS1 Inhibitors: Recent Advances and Perspectives

Y Zeng, X Ren, P Jin, Y Zhang, M Zhuo… - Journal of Medicinal …, 2023 - ACS Publications
… (B) Magnified view of the upper dashed box in A, showing a … Although BubR1 evolved into
a typical pseudokinase in … exists a set of additional kinases such as Polo-like Kinase 1 (PLK1), …

[图书][B] Adverse events and oncotargeted kinase inhibitors

G Tridente - 2017 - books.google.com
… The brief introductory drug history essentially focuses on the safety profile evolution during
the first years of postmarketing observation, which gives an idea of the safety status foreach …

[PDF][PDF] Role of PKCepsilon in cell division and differentiation: implication for genomic instability and autoimmunity

S Martini - 2017 - repository.unipr.it
Plks also affect both Cdc25 and Myt1(and presumably Wee1), but whether they function as
trigger … To guard against chromosome missegregation, cells have evolved a surveillance …

Fecal microbiota transplantation from warthog to pig confirms the influence of the gut microbiota on African swine fever susceptibility

J Zhang, F Rodríguez, MJ Navas, M Costa-Hurtado… - Scientific reports, 2020 - nature.com
… piglets, placed in 4 independent boxes with individual ventilation and maintained in … crypt
depth from ileum and crypt depth from colon were assessed on 10 well-oriented villi and crypts

[PDF][PDF] Aging is selected for, adaptive, and programmed. 19. The cellular senescence program

K Heininger - researchgate.net
evolution and cell biology, including the development of his influential theory of the germ
plasm, Weismann produced, beginning in 1881, several essays on the evolutionary … of opinion (…