Genetic polymorphisms influence on the response to clopidogrel in peripheral artery disease patients following percutaneous transluminal angioplasty

X Díaz-Villamarín, CL Dávila-Fajardo… - …, 2016 - Future Medicine
… is limited by MDR1, which is an … of Spanish peripheral artery disease patients following
PTA and a meta-analysis was performed combining our results for CYP2C19*2 polymorphism

Methotrexate pharmacokinetic genetic variants are associated with outcome in rheumatoid arthritis patients

P Moya, J Salazar, MJ Arranz, C Díaz-Torné… - …, 2016 - Future Medicine
… whether polymorphisms in pharmacokinetic genes are … , several studies have analyzed the
rs1045642 variant (C3435T) in … in the southern Spanish population with rheumatoid arthritis. …

Pharmacogenetic aspects of the use of tacrolimus in renal transplantation: recent developments and ethnic considerations

JT Tang, LM Andrews, T van Gelder… - Expert opinion on …, 2016 - Taylor & Francis
… is explained by genetic polymorphisms in genes encoding for Tac … shown to be present
in 1.2% of the Spanish population. This … of the CYP3A4, CYP3A5, and MDR-1 genes and …

Interethnic differences in the prevalence of main cardiovascular pharmacogenetic biomarkers

K Mirzaev, S Abdullaev, K Akmalova… - …, 2020 - Future Medicine
… at the University of Florida, where CYP2C19 gene polymorphism testing is performed for all
… well as at Vanderbilt University, where SLCO1B1 gene polymorphism is tested before statin …

Pharmacogenetic biomarkers predictive of the pharmacokinetics and pharmacodynamics of immunosuppressive drugs

N Picard, S Bergan, P Marquet… - Therapeutic drug …, 2016 - journals.lww.com
… However, despite some evidence of clear associations between polymorphisms in genes
encoding metabolizing enzymes (CYP3A4/3A5, UGT1A9) or drug transporters (ABCB1, ABCC2…

[HTML][HTML] Insights into the pharmacogenetics of tacrolimus pharmacokinetics and pharmacodynamics

M Brunet, M Pastor-Anglada - Pharmaceutics, 2022 - mdpi.com
… More recently, several genetic polymorphisms in selected SLC and ABC transporter … C3435T,
it has been unequivocally demonstrated that this SNP is associated with decreased MDR1

[HTML][HTML] Pharmacogenetics and Schizophrenia—Can Genomics Improve the Treatment with Second-Generation Antipsychotics?

O Płaza, P Gałecki, A Orzechowska, M Gałecka… - Biomedicines, 2022 - mdpi.com
… The C3435T polymorphism was also associated with lower clearance and volume of …
different—Belmonte research included healthy Spanish volunteers, whereas Suzuki analyzed the …

[HTML][HTML] Pharmacogenetic landscape of Metabolic Syndrome components drug response in Tunisia and comparison with worldwide populations

H Jmel, L Romdhane, Y Ben Halima, M Hechmi… - PLoS …, 2018 - journals.plos.org
genetic variants were chosen from published polymorphisms … variant located on ABCB1
(MDR1) gene which is one of … research showed that the ABCB1 C3435T genotype influences the …

Frequency of CYP2B6 Alleles in Major Iranian Ethnicities, Affecting Response to Efavirenz

P Mardi, B Tavakoli-Far, SS Nia, R Jazayeri… - Genetics …, 2022 - cambridge.org
… humans is encoded by the CYP2B6 gene. Polymorphisms of this gene play a crucial role in
… frequencies of the CYP2B6 gene between Spaniards and Central Americans. ey showed …

[HTML][HTML] Pharmacogenetics of amfepramone in healthy Mexican subjects reveals potential markers for tailoring pharmacotherapy of obesity: results of a randomised …

M Gómez-Silva, E Piñeyro-Garza, R Vargas-Zapata… - Scientific reports, 2019 - nature.com
… Influence of ABCB1 C3435T polymorphism on the pharmacokinetics of lansoprazole and …
A variant 2677A allele of the MDR1 gene affects fexofenadine disposition. Clinical …