Polymorphs, solvatomorphs, hydrate, and perhydrate of dabrafenib

SK Rai, A Gunnam, GJO Beran, JA Kaduk… - Crystal Growth & …, 2023 - ACS Publications
… With its high molecular flexibility, prolific solvate potential, and drug polymorphism, the
present work opens the opportunity for further solid-form landscape study of the popular …

Water and the relationship to the crystal structure stability of azithromycin: Thermal investigations of solvatomorphism, amorphism and polymorphism

R Neglur, E Hosten, M Aucamp, W Liebenberg… - Journal of Thermal …, 2018 - Springer
This study investigated the solid-state physical stabilities of azithromycin dihydrate (AZM-DH),
thermally prepared anhydrate and hemihydrate modifications. Programmed thermal …

First evidence of polymorphism in furosemide solvates

AA Beloborodova, VS Minkov, DA Rychkov… - Crystal Growth & …, 2017 - ACS Publications
Polymorphism is very important for chemical sciences and technology since properties of
different polymorphs may differ. (1, 2) Multiple local energy minima corresponding to different …

Structural and Computational Study of 4 New Solvatomorphs of Betulin: A Combined X-Ray, Hirshfeld Surface, and Thermal Analysis

D Yang, N Gong, L Zhang, Y Lu, G Du - Journal of Pharmaceutical Sciences, 2017 - Elsevier
… We observed marked solvatomorphism during crystallization … Similar to polymorphism,
solvatomorphism is commonly observed in … Polymorphism and solvatomorphism 2010

Solvatochromism and reversible solvent exchange phenomena in solvatomorphic organic chromophore crystals

KK Jha, A Kumar, P Munshi - Crystal Growth & Design, 2023 - ACS Publications
Solvatomorphs or solvates are common in pharmaceutical compounds, and
solvatochromism is often reported in solution. The present study reports eight solvates of (Z)-3-(3-hydroxy-4-…

Isomorphic Channel-type pseudopolymorphs of azathioprine: From structural confirmations to a rational polymorph screening approach

D Samohvalov, MA Lungan, S Shova… - Crystal Growth & …, 2021 - ACS Publications
… (1,9) Thus, while polymorphism refers to the crystal systems … elemental composition,
solvatomorphism denotes systems where … By taking another step further, alongside polymorphism, …

[HTML][HTML] Solvatomorphism of moxidectin

T Grell, M Barbero, F Pattarino, GB Giovenzana… - Molecules, 2021 - mdpi.com
Polymorphism and solvatomorphism are highly important phenomena in the pharmaceutical
industry [1,2]. Different arrangements of the molecules of an active pharmaceutical …

[HTML][HTML] Solvatomorphism in (Z)-4-fluoro-N′-(3-fluorophenyl) benzimidamide: the role of intermolecular O–H⋯ F interaction

D Dey, D Chopra - CrystEngComm, 2016 - pubs.rsc.org
… In the current study, as part of our investigation into the polymorphic characteristics of
fluorinated phenyl benzimidamides, we have observed the solvatomorph formation in (Z)-4-fluoro-N…

4-METHYL HYPPURIC ACID: A CASE OF POLYMORPHISM AND SOLVATOMORPHISM.

GE Delgado, M Guillen, AJ Mora - Periódico Tchê Química, 2019 - search.ebscohost.com
Polymorphism is known as the ability of a solid material to exist in … Polymorphism is of
particular importance in industrial processes, where different physical properties of polymorphic

Polymorphs and versatile solvates of 7-hydroxyisoflavone

N Gong, G Zhang, G Jin, G Du, Y Lu - Journal of Pharmaceutical Sciences, 2016 - Elsevier
Polymorphism is frequently defined as the ability of a substance to exist as 2 or more … as
the reference pattern in the solvatomorphic identification. Different solvent molecules result in …