Porphyromonas gingivalis initiates a mesenchymal‐like transition through ZEB1 in gingival epithelial cells

MN Sztukowska, A Ojo, S Ahmed… - Cellular …, 2016 - Wiley Online Library
… that bind to 5′-CACCTG sequences and repress transcription of … gingivalis fimbriae that
converge on Zeb1 remain to be … epithelial marker cytokeratin 7 (KRT7) were unaffected by P. …

Peptide-based inhibitors of fimbrial biogenesis in Porphyromonas gingivalis

SR Alaei, JH Park, SG Walker… - Infection and …, 2019 - Am Soc Microbiol
… assembly through a donor strand exchange mechanism, in which cleavage of the N-terminal
proregion opens an interactive surface for binding of a C-terminal donor strand from a …

[HTML][HTML] Porphyromonas gingivalis FimA and Mfa1 fimbriae: Current insights on localization, function, biogenesis, and genotype

Y Hasegawa, K Nagano - Japanese Dental Science Review, 2021 - Elsevier
… In general, the periodontal pathogen Porphyromonas gingivalis expresses distinct … fimbriae
may be responsible for the adhesive properties of P. gingivalis and enable it to bind host cells

[HTML][HTML] Oral mucosal epithelial cells

S Groeger, J Meyle - Frontiers in immunology, 2019 - frontiersin.org
… pathogenic bacteria such as Porphyromonas gingivalis (P. … specialized epithelial cells within
the gingiva show a distinct keratingingivalis fimbriae bind to cellular α5β1-integrin, which …

The interaction of Porphyromonas gingivalis with host epithelial cells and its relevance to periodontal disease

FBH Al-Taweel - 2017 - etheses.whiterose.ac.uk
… is not fully characterized but the interaction of P. gingivalis fimbriae with both fibronectin
and the fibronectin-binding receptor, α5β1 integrin, is thought to play a role in the invasion …

Role of Porphyromonas gingivalis in oral squamous cell carcinoma development: A systematic review

I Lafuente Ibáñez de Mendoza… - Journal of …, 2020 - Wiley Online Library
epithelial cells (Population) infected with P gingivalis (Intervention), compared to non-infected
OSCC or healthy oral epithelial cells (… of P gingivalis varied depending on fimA fimbriae. …

Porphyromonas gingivalis enhances pneumococcal adhesion to human alveolar epithelial cells by increasing expression of host platelet‐activating factor receptor

N Kamio, M Hayata, M Tamura, H Tanaka, K Imai - FEBS letters, 2021 - Wiley Online Library
… Bacterial binding to the epithelium subsequently causes … In addition, keratin 10, polymeric
immunoglobulin receptor and … We investigated three major components of CSP: LPS, fimbriae

[HTML][HTML] Pathogenesis of Important Virulence Factors of Porphyromonas gingivalis via Toll-Like Receptors

L Jia, N Han, J Du, L Guo, Z Luo, Y Liu - Frontiers in cellular and …, 2019 - frontiersin.org
… pathway on cell activity depends on mainly the binding of … Porphyromonas gingivalis long
fimbrial proteins were capable … gingivalis by epithelial cells, mCD14 can cause a more violent …

Localization and density of Porphyromonas gingivalis and Tannerella forsythia in gingival and subgingival granulation tissues affected by chronic or aggressive …

GA Rajakaruna, M Negi, K Uchida, M Sekine… - Scientific reports, 2018 - nature.com
… cytoplasm, which was detected using the anti-cytokeratin … is associated with cell molecules;
such as major fimbriae protein (… The ability of TF to attach to and invade epithelial cells is …

Porphyromonas gingivalis can invade periodontal ligament stem cells

C Pan, J Liu, H Wang, J Song, L Tan, H Zhao - BMC microbiology, 2017 - Springer
… , gingipains and fimbriae, not only directly destroy periodontal tissue but also cause secondary
… However, intermediate filaments differ among cells, such as keratin in epithelial cells, …