The μ1-opioid receptor and 5-HT2A-and 5HT2C-serotonergic receptors of the locus coeruleus are critical in elaborating hypoalgesia induced by tonic and tonic–clonic …

RL de Freitas, P Medeiros, JA da Silva, RC de Oliveira… - Neuroscience, 2016 - Elsevier
… assess the role of LC neurons in the modulation of post-ictal … to address the ultimate control
of pain due to the modulation of … the neurochemical mechanism of post-ictal antinociception …

Dorsal raphe nucleus acetylcholine-mediated neurotransmission modulates post-ictal antinociception: The role of muscarinic and nicotinic cholinergic receptors

RC de Oliveira, R de Oliveira, AF Biagioni… - Brain Research, 2016 - Elsevier
… Although the DRN is rich in serotoninergic neurons, cholinergic neurons are also found in …
by post-ictal analgesia. The present study investigated the role of cholinergic mechanisms in …

… and muscarinic cholinergic receptors are recruited by acetylcholine-mediated neurotransmission within the locus coeruleus during the organisation of post-ictal …

RC de Oliveira, R de Oliveira, AF Biagioni… - Brain Research …, 2016 - Elsevier
Post-ictal analgesia recruits muscarinic cholinergic receptors … study investigated the role of
cholinergic mechanisms of the LC in … μ1-opioid receptor to modulate post-ictal antinociception …

µ1Opioid receptors in the dorsomedial and ventrolateral columns of the periaqueductal grey matter are critical for the enhancement of postictal antinociception

RL de Freitas, P Medeiros, AU Khan, NC Coimbra - Synapse, 2016 - Wiley Online Library
… to induce analgesia. Thus, the aim of this investigation was to evaluate the … muscarinic and
nicotinic cholinergic receptors in an … In addition, our research group showed that serotonergic

The epileptic gerbil. Neuronal networks and actions of antiepileptic drugs

W Löscher - Drugs for the Control of Epilepsy, 2019 - taylorfrancis.com
… In general, the role of cholinergic neurons in genetic animal … that the brain content of serotonin
(5-hydroxytryptamine; 5-HT) … respect to opioid antagonists and post-ictal refractoriness in …

GABAergic and glutamatergic inputs to the medulla oblongata and locus coeruleus noradrenergic pathways are critical for seizures and postictal antinociception …

M Mendonça-dos-Santos, TCT Gonçalves… - Scientific Reports, 2024 - nature.com
… , such as the locus coeruleus; and in acetylcholine 19 , such as the … The goal of this work was
to investigate the role of the NTS in … of the endogenous pain modulatory descending system …

[HTML][HTML] Neurotoxic lesions of the pedunculopontine tegmental nucleus impair the elaboration of postictal antinociception

RC de Oliveira, R de Oliveira, LL Falconi-Sobrinho… - Physiology & …, 2018 - Elsevier
… evidence indicates that the cholinergic system plays an important role in the … participation
of other neurotransmitters, such as serotonin [11,12,16], noradrenaline [8], endogenous opioid

Does pain sensitivity increase during ictal period? Evidence from absence epileptic WAG/Rij rats

SK Velioglu, O Gedikli, M Yıldırım, A Ayar - Epilepsy & Behavior, 2018 - Elsevier
… in chronic pain conditions, the results of this study warrant further investigation of … mechanisms
involved in this increased pain sensitivity. A better understanding of these mechanisms

[PDF][PDF] Microglial and neurochemical mechanisms of seizure-induced central autonomic cardiovascular dysfunction

AM Bhandare - 2022 - figshare.mq.edu.au
… neurotransmitter in the RVLM, plays an important role in the development of seizures. The
major aims of this thesis were to investigate the role of microglia, PACAP and glutamate in the …

Ventrolateral periaqueductal gray matter neurochemical lesion facilitates epileptogenesis and enhances pain sensitivity in epileptic rats

L Wang, J Shen, XT Cai, WW Tao, YD Wan, DL Li… - Neuroscience, 2019 - Elsevier
… This indicates an involvement of the pain regulating structure, … could be a possible underlying
mechanism of the interactive … neurons, leading to post-ictal analgesia occurrence as vlPAG …