[HTML][HTML] The importance of poly (ethylene glycol) alternatives for overcoming PEG immunogenicity in drug delivery and bioconjugation

TT Hoang Thi, EH Pilkington, DH Nguyen, JS Lee… - Polymers, 2020 - mdpi.com
… size of PEG-modified NPs to protect them from renal clearance, as … drugs can lead to the
production of anti-PEG antibodies (anti-… By varying PEG surface densities, the circulation time of …

Versatile bioconjugation strategies of PEG-modified upconversion nanoparticles for bioanalytical applications

U Kostiv, Z Farka, MJ Mickert, HH Gorris… - …, 2020 - ACS Publications
… Here, we have prepared NIR-excitable UCNPs that are long-term colloidally stable in
buffered media and possess functional groups. Heterobifunctional poly(ethylene glycol) (PEG) …

Poly (ethylene glycol) Cross-Linked Antibody Nanoparticles for Tunable Biointeractions

Y Hu, C Cortez-Jugo, Y Ju, T Zheng, J Zhou… - Chemistry of …, 2023 - ACS Publications
… Recent studies have shown that varying nanoparticle … used to prepare PEGylated antibody
nanoparticles (designated as … -linkers provided varying degrees of protection to the antibodies …

A nanoparticle platform to evaluate bioconjugation and receptor-mediated cell uptake using cross-linked polyion complex micelles bearing antibody fragments

S Florinas, M Liu, R Fleming… - …, 2016 - ACS Publications
… (B) Optimization of PIC micelle formation by varying ratios of … chemistry for preparation of
stable bioconjugates. In the … -linker for preparation of functional nanoparticles in this work …

[HTML][HTML] Bioconjugate therapeutics: current progress and future perspective

F Li, RI Mahato - Molecular pharmaceutics, 2017 - ACS Publications
… carrier molecules, bioconjugate therapeutics are considered … which involves the conjugation
of poly(ethylene glycol) (PEG) … Bioconjugates prepared with many other polymers, such as N…

Polyglycerol and poly (ethylene glycol) exhibit different effects on pharmacokinetics and antibody generation when grafted to nanoparticle surfaces

K Shin, HW Suh, J Grundler, AY Lynn, JU Pothupitiya… - Biomaterials, 2022 - Elsevier
… , we prepared NPs with varying surface densities … synthesis of linear PG was performed by
ring-opening polymerization with ethoxyethyl glycidyl ether (EEGE, hydroxyl group-protected

Folic acid-conjugated pH and redox-sensitive ellipsoidal hybrid magnetic nanoparticles for dual-triggered drug release

G Birlik Demirel, E Aygul, A Dag, S Atasoy… - ACS Applied Bio …, 2020 - ACS Publications
… ligand (folic acid-conjugated poly(ethylene glycol), FA–PEG) … In this study, the prepared
nanoparticles have an ellipsoidal … between 30 and 10.1% for varying amounts of DTT from 0 to …

Nanoengineering of Poly (ethylene glycol) Particles for Stealth and Targeting

J Cui, M Björnmalm, Y Ju, F Caruso - Langmuir, 2018 - ACS Publications
… Our work complements other approaches that have been developed for preparing PEG-…
MDA-MB-231 cell line could be tuned by varying the ratio of HA and PEG in the capsules. When …

Polymerization of ethylene oxide, propylene oxide, and other alkylene oxides: synthesis, novel polymer architectures, and bioconjugation

J Herzberger, K Niederer, H Pohlit, J Seiwert… - Chemical …, 2016 - ACS Publications
… , Staudinger and Schweitzer prepared a series of poly(ethylene glycol) samples from …
protecting groups, the hydroxyl moieties are addressable for further reactions, eg, bioconjugation

Tuning the optical properties of poly (p-phenylene ethynylene) nanoparticles as bio-imaging probes by side chain functionalization

L D'Olieslaeger, Y Braeken, S Cheruku, J Smits… - Journal of colloid and …, 2017 - Elsevier
… , enabling different bioconjugation and targeting strategies. … For diethynyl monomer 8, two
trimethylsilyl (TMS) protected … different PPE polymers with varying side chain patterns using …