… into dense deposit disease (DDD) and C3 glomerulonephritis (… can be observed in both
entities [11,15,33]. In PIGN, the … We chose to include both primary and secondary MPGN cases in …

… entity, 3 showing isolated C3 without very dense deposits. The … in C3 glomerulopathy include
genetic and acquired factors. … In a study of over 300 patients with primary MPGN, the group …

… The stepwise formation of convertases from isolated complement … into Dense Deposit Disease
(DDD) and C3 glomerulonephritis (… A genetic and protein approach to study the Factor H-…

… , atypical haemolytic uraemic syndrome and a new entity called C3 … glomerular diseases in
which the primary pathogenic process is a … . Glomerulonephritis with isolated C3 deposits and …

… , dense deposit disease and the more recently described C3 … the clinical picture of this new
disease entity, we suggest that in … to primary membranoproliferative glomerulonephritis of all …

… of primary glomerulonephritis globally, and a common cause … dense deposits: type I, type
II or Dense Deposit Disease (… Risk factors for recurrence of C3 glomerulopathy after renal …

… of factor H or C3 genes increased the risk of developing the … nephritic syndrome (16 to 38
percent), isolated macroscopic … two disorders are thought to share a common pathogenesis [71]…

… of IgM, C3, and C1q deposits in the mesangium … disease spectrum. Uncontrolled activation
of the alternate complement pathway resulting from mutations of factor H gene or anti-factor H …

… The term aHUS is applied to a heterogenous group of diseases (Figure ​1) that share TMA
… in atypical hemolytic uremic syndrome, dense deposit disease, and C3 glomerulonephritis …

… —dense deposit disease (DDD) and C3 glomerulonephritis (… microscopy, distinction between
the two entities is made by EM [3]. … serologic and genetic testing for inherited and acquired …