Expectation effects on brain dopamine responses to methylphenidate in cocaine use disorder
… when rewards are less than expected (blunted DA increases … second scan on a given day)
to avoid the pharmacological … in active CUD subjects expanded prior findings of decreased …
to avoid the pharmacological … in active CUD subjects expanded prior findings of decreased …
A single, extinction-based treatment with a kappa opioid receptor agonist elicits a long-term reduction in cocaine relapse
JA Heinsbroek, AB Furbish, J Peters - Neuropsychopharmacology, 2018 - nature.com
… prior to the cocaine priming injection and significant cocaine-… the rewarding memory of the
cocaine cues to reduce cocaine … of a cocaine conditioned place preference memory [44]. It is …
cocaine cues to reduce cocaine … of a cocaine conditioned place preference memory [44]. It is …
HDAC5 and its target gene, Npas4, function in the nucleus accumbens to regulate cocaine-conditioned behaviors
… significantly reduced cocaine conditioned place preference … cocaine-stimulated target genes
that promote cocaine reward-… GABAergic interneurons, it increases glutamatergic synapses. …
that promote cocaine reward-… GABAergic interneurons, it increases glutamatergic synapses. …
Striatal RGS7 regulates depression-related behaviors and stress-induced reinstatement of cocaine conditioned place preference
… reflected general changes in reward setpoint common across … but not for cocaine agree
with previous studies that have … This raises an intriguing notion that Rgs7 may be a general …
with previous studies that have … This raises an intriguing notion that Rgs7 may be a general …
Whole-brain tracking of cocaine and sugar rewards processing
Ł Bijoch, J Klos, M Pawłowska, J Wiśniewska… - Translational …, 2023 - nature.com
… of rewards was similar, after prolonged exposure, cocaine … that both sucrose and cocaine
exposure increases the number of … pre-trained to lever-press or nose-poke to obtain the reward. …
exposure increases the number of … pre-trained to lever-press or nose-poke to obtain the reward. …
A place for the hippocampus in the cocaine addiction circuit: Potential roles for adult hippocampal neurogenesis
… (eg, an affective state preceding drug use, a song playing … (B) The cocaine-induced
conditioned place preference (CPP… ie, the rewarding value elicited by these stimuli or by cocaine …
conditioned place preference (CPP… ie, the rewarding value elicited by these stimuli or by cocaine …
Once is too much: Early development of the opponent process in taste reactivity behavior is associated with later escalation of cocaine self-administration in rats
EM Colechio, DN Alexander, CG Imperio… - Brain research …, 2018 - Elsevier
… it is followed by a much more rewarding stimulus (ie, the drug). … prior to each daily session
by diluting 4.0 ml of cocaine HCl … in the analysis of extended-access data by other laboratories, …
by diluting 4.0 ml of cocaine HCl … in the analysis of extended-access data by other laboratories, …
Escalated cocaine “binges” in rats: enduring effects of social defeat stress or intra-VTA CRF
… This raises the question of whether CRF alone is sufficient to … defeat or CRF microinfusion
on cocaine reward valuation, in order … of CRF into the VTA prior to self-administration training …
on cocaine reward valuation, in order … of CRF into the VTA prior to self-administration training …
Conditioned stress prevents cue-primed cocaine reinstatement only in stress-responsive rats
… The use of an initial ShA component prior to LgA cocaine self-… We used the threshold cycle
results for the samples to … -prolonged-stressor (SPS) model in combination with cocaine self-…
results for the samples to … -prolonged-stressor (SPS) model in combination with cocaine self-…
[PDF][PDF] Intermittent abstinence potentiates oxycodone self-administration under extended access conditions and alters brain reward sensitivity
… Pre-IVSA brain reward thresholds increased with sequential daily LgA IVSA sessions, …
abstinence (reflects averages of the 4 sessions immediately before (Pre) and after (Post) the …
abstinence (reflects averages of the 4 sessions immediately before (Pre) and after (Post) the …