[HTML][HTML] Angiotensin-I-converting enzyme inhibitory peptides in milk fermented by indigenous lactic acid bacteria
YT Rubak, L Nuraida, D Iswantini… - Veterinary …, 2020 - ncbi.nlm.nih.gov
Materials and Methods: Reconstituted milk (11%) inoculated with ten LAB isolates, and then
incubated at 37 C until it reaches pH 4.6. The evaluation was carried out for LAB count, lactic
acid concentration, peptide content, and ACE-I activity. The low molecular weight (MW)
peptides (< 3 kDa) were identified using Nano LC Ultimate 3000 series system Tandem Q
Exactive Plus Orbitrap high-resolution mass spectrometry. Results: The result showed that
the ten LAB isolates were able to produce ACE-I in fermented milk with the activities in the …
incubated at 37 C until it reaches pH 4.6. The evaluation was carried out for LAB count, lactic
acid concentration, peptide content, and ACE-I activity. The low molecular weight (MW)
peptides (< 3 kDa) were identified using Nano LC Ultimate 3000 series system Tandem Q
Exactive Plus Orbitrap high-resolution mass spectrometry. Results: The result showed that
the ten LAB isolates were able to produce ACE-I in fermented milk with the activities in the …
Production of Angiotensin-I-Converting-Enzyme-Inhibitory Peptides in Fermented Milks (Lassi) Fermented by Lactobacillus acidophillus with Consideration of …
PV Padghan, B Mann, R Sharma, R Bajaj… - … Journal of Peptide …, 2017 - Springer
The lassi, fermented milks product containing angiotensin-I-converting-enzyme (ACE)-
inhibitory peptides were produced by using selected Lactobacillus acidophilus NCDC-15
and the incubation period and simmering effect was also optimized for production of ACE-
inhibitory peptides. The time–temperature combination for the heat treatment was optimized
using RSM. The biological activity was measured in the supernatant of the fermented milk
after centrifugation. The lowest IC 50 values for the inhibition of angiotensin-converting …
inhibitory peptides were produced by using selected Lactobacillus acidophilus NCDC-15
and the incubation period and simmering effect was also optimized for production of ACE-
inhibitory peptides. The time–temperature combination for the heat treatment was optimized
using RSM. The biological activity was measured in the supernatant of the fermented milk
after centrifugation. The lowest IC 50 values for the inhibition of angiotensin-converting …
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