Principles of DNA methylation and their implications for biology and medicine

Y Dor, H Cedar - The Lancet, 2018 - thelancet.com
… In this Review we provide a map of the DNA methylation landscape, present the logic for how
these patterns are established and maintained … Programming of DNA methylation patterns. …

Impact of DNA methylation programming on normal and pre-leukemic hematopoiesis

J Langstein, MD Milsom, DB Lipka - Seminars in cancer biology, 2018 - Elsevier
… of methylation in regulating cellular function and phenotypes [17], [18], [19]. However, our
understanding of genome-wide methylation patterns … maps of DNA methylation using whole-…

DNA methylation in cancer and aging

M Klutstein, D Nejman, R Greenfield, H Cedar - Cancer research, 2016 - AACR
… in setting up normal DNA methylation patterns and understanding how … Aberrant DNA
methylation in cancer can be generated either prior to … Programming of DNA methylation patterns

[HTML][HTML] DNA methylation reprogramming during mammalian development

Y Zeng, T Chen - Genes, 2019 - mdpi.com
… (5-methylcytosine, 5mC) is a major form of DNA modification in the mammalian genome …
, DNA methylation is stably maintained in somatic tissues. However, DNA methylation patterns

Analysis of the epigenetic signature of cell reprogramming by computational DNA methylation profiles

Y Zuo, M Song, H Li, X Chen, P Cao… - Current …, 2020 - ingentaconnect.com
Background: DNA methylation plays an important role in the reprogramming process. …
genome-wide DNA methylation data from different cell lines, comparative methylation profiles were …

Tools and strategies for analysis of genome-wide and gene-specific DNA methylation patterns

A Chatterjee, EJ Rodger, IM Morison… - Oral Biology: Molecular …, 2017 - Springer
DNA methylation is a stable epigenetic mechanism that has … of normal and altered DNA
methylation patterns are important to … methodologies to investigate DNA methylation. The …

The role of DNA methylation in hypertension

M Demura, K Saijoh - Hypertension: from basic research to clinical …, 2017 - Springer
… Intrauterine programming involves drastic changes in DNA methylation … through alteration
of DNA methylation patterns. These factors are likely to alter DNA methylation patterns in all …

[HTML][HTML] DNA methylation of the promoter region of bnip3 and bnip3l genes induced by metabolic programming

V Veron, L Marandel, J Liu, EJ Vélez, O Lepais… - BMC genomics, 2018 - Springer
… Collectively, we highlighted in this study modifications of DNA methylation levels of bnip3a
and bnip3lb1 genes in a context of metabolic programming. An interesting zone has been …

Dynamic DNA methylation: In the right place at the right time

C Luo, P Hajkova, JR Ecker - Science, 2018 - science.org
… In instances in which DNA methylation is globally reduced as a part of a normal developmental
program, no aberrant transcriptional activation is observed, suggesting an alternative or …

[HTML][HTML] A comparative methylome analysis reveals conservation and divergence of DNA methylation patterns and functions in vertebrates

H Al Adhami, AF Bardet, M Dumas, E Cleroux… - BMC biology, 2022 - Springer
DNA methylation varies among species. We analyze the evolutionary conservation of DNA
methylation patterns … of DNA methylation in vertebrate cells by DNA methylation inhibition. …