Principles of DNA methylation and their implications for biology and medicine
… In this Review we provide a map of the DNA methylation landscape, present the logic for how
these patterns are established and maintained … Programming of DNA methylation patterns. …
these patterns are established and maintained … Programming of DNA methylation patterns. …
Impact of DNA methylation programming on normal and pre-leukemic hematopoiesis
… of methylation in regulating cellular function and phenotypes [17], [18], [19]. However, our
understanding of genome-wide methylation patterns … maps of DNA methylation using whole-…
understanding of genome-wide methylation patterns … maps of DNA methylation using whole-…
DNA methylation in cancer and aging
M Klutstein, D Nejman, R Greenfield, H Cedar - Cancer research, 2016 - AACR
… in setting up normal DNA methylation patterns and understanding how … Aberrant DNA
methylation in cancer can be generated either prior to … Programming of DNA methylation patterns …
methylation in cancer can be generated either prior to … Programming of DNA methylation patterns …
[HTML][HTML] DNA methylation reprogramming during mammalian development
Y Zeng, T Chen - Genes, 2019 - mdpi.com
… (5-methylcytosine, 5mC) is a major form of DNA modification in the mammalian genome …
, DNA methylation is stably maintained in somatic tissues. However, DNA methylation patterns …
, DNA methylation is stably maintained in somatic tissues. However, DNA methylation patterns …
Analysis of the epigenetic signature of cell reprogramming by computational DNA methylation profiles
Background: DNA methylation plays an important role in the reprogramming process. …
genome-wide DNA methylation data from different cell lines, comparative methylation profiles were …
genome-wide DNA methylation data from different cell lines, comparative methylation profiles were …
Tools and strategies for analysis of genome-wide and gene-specific DNA methylation patterns
… DNA methylation is a stable epigenetic mechanism that has … of normal and altered DNA
methylation patterns are important to … methodologies to investigate DNA methylation. The …
methylation patterns are important to … methodologies to investigate DNA methylation. The …
The role of DNA methylation in hypertension
M Demura, K Saijoh - Hypertension: from basic research to clinical …, 2017 - Springer
… Intrauterine programming involves drastic changes in DNA methylation … through alteration
of DNA methylation patterns. These factors are likely to alter DNA methylation patterns in all …
of DNA methylation patterns. These factors are likely to alter DNA methylation patterns in all …
[HTML][HTML] DNA methylation of the promoter region of bnip3 and bnip3l genes induced by metabolic programming
… Collectively, we highlighted in this study modifications of DNA methylation levels of bnip3a
and bnip3lb1 genes in a context of metabolic programming. An interesting zone has been …
and bnip3lb1 genes in a context of metabolic programming. An interesting zone has been …
Dynamic DNA methylation: In the right place at the right time
… In instances in which DNA methylation is globally reduced as a part of a normal developmental
program, no aberrant transcriptional activation is observed, suggesting an alternative or …
program, no aberrant transcriptional activation is observed, suggesting an alternative or …
[HTML][HTML] A comparative methylome analysis reveals conservation and divergence of DNA methylation patterns and functions in vertebrates
H Al Adhami, AF Bardet, M Dumas, E Cleroux… - BMC biology, 2022 - Springer
… DNA methylation varies among species. We analyze the evolutionary conservation of DNA
methylation patterns … of DNA methylation in vertebrate cells by DNA methylation inhibition. …
methylation patterns … of DNA methylation in vertebrate cells by DNA methylation inhibition. …
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