Recent progress in microRNA-based delivery systems for the treatment of human disease

Y Fu, J Chen, Z Huang - ExRNA, 2019 - Springer
… Here, we introduce four widely used viral vectors for miRNA delivery including
adenovirus vectors, adeno-associated virus vectors, retroviral vectors, and lentivirus vectors. …

Current progress of miRNA-derivative nucleotide drugs: modifications, delivery systems, applications

C Asakiya, L Zhu, J Yuhan, L Zhu… - … on Drug Delivery, 2022 - Taylor & Francis
… nanocarriers to overcome specific delivery challenges. In this review, the researchers
discussed four central miRNA delivery systems: self-assembled miRNA nanocarriers, exosome-…

Recent advances in miRNA delivery systems

I Dasgupta, A Chatterjee - Methods and protocols, 2021 - mdpi.com
… Concerted efforts from academic research laboratories and pharmaceutical companies
bolstered the progress of miRNA-based drug candidates to clinical trials for the treatment of …

A comprehensive review of cancer MicroRNA therapeutic delivery strategies

A Forterre, H Komuro, S Aminova, M Harada - Cancers, 2020 - mdpi.com
… significant hurdles in therapeutic miRNA usage are the stability and the delivery system. In
… of therapeutic miRNA delivery systems that includes virus-based delivery, non-viral delivery (…

Therapeutic microRNA delivery strategies with special emphasis on cancer therapy and tumorigenesis: current trends and future challenges

C Chakraborty, ZH Wen… - Current drug …, 2016 - ingentaconnect.com
miRNA is no equivalent to DNA delivery and siRNA delivery, and some differences are
noticed. However, significant progress has been made for the delivery of miRNA. It is predictable …

Current progress on microRNAs‐based therapeutics in neurodegenerative diseases

P Pereira, JA Queiroz, A Figueiras… - Wiley Interdisciplinary …, 2017 - Wiley Online Library
… of miRNA therapeutics for brain targeting are discussed. In particular, this review highlights
current knowledge and progress … Finally, the available miRNA delivery systems are reviewed …

MicroRNA replacement therapy in cancer

H Mollaei, R Safaralizadeh… - Journal of cellular …, 2019 - Wiley Online Library
… The systemic miRNA delivery strategy is a significant progress to overcome the limitation of
miRNA delivery in … Up to now, different systemic delivery approaches have been developed. …

MicroRNA therapeutics in cancer: current advances and challenges

S Reda El Sayed, J Cristante, L Guyon, J Denis… - Cancers, 2021 - mdpi.com
… We cover the approaches implemented for the delivery of miRNA mimics or anti-miRNAs (antimiRs)
with an emphasis on nanotechnology-based formulations for the treatment of major …

Advances in the discovery of microRNA-based anticancer therapeutics: latest tools and developments

KKW To, W Fong, CWS Tong, M Wu… - Expert opinion on …, 2020 - Taylor & Francis
… site-specific delivery of novel miRNAmiRNA or miRNA family members sharing the same
seed region. Various non-viral or viral-based vector systems have been used to deliver miRNA

[HTML][HTML] Exosome-based small RNA delivery: Progress and prospects

M Lu, H Xing, Z Xun, T Yang, P Ding, C Cai… - Asian journal of …, 2018 - Elsevier
progress and challenges of RNAi therapy, and discuss the potential of exosomes' applications
in small RNA deliverydelivery of miRNA. Recently, another research group evaluated the …