Nanocarriers for microRNA delivery in cancer medicine

I Fernandez-Piñeiro, I Badiola, A Sanchez - Biotechnology advances, 2017 - Elsevier
… Furthermore, current progress in understanding the molecular pathways and functions of …
In this review, we will cover nanosystems for microRNA (miRNA) delivery developed to date …

Strategies to modulate microRNA functions for the treatment of cancer or organ injury

TJ Lee, X Yuan, K Kerr, JY Yoo, DH Kim, B Kaur… - Pharmacological …, 2020 - ASPET
… inhibitors and highlights current progress in miRNA-based disease therapy that has … in
miRNA delivery, we believe that additional therapeutic approaches to modulate miRNA function …

[HTML][HTML] miRNA delivery by nanosystems: state of the art and perspectives

FC Moraes, C Pichon, D Letourneur, F Chaubet - Pharmaceutics, 2021 - mdpi.com
miRNA or miRNA expression vectors to induce expression of a miRNA in cells and the delivery
of the miRNA … Despite significant progress in the field of non-viral vehicles, the discovery …

Nanoparticles Mediated Gene Knockout Through miRNA Replacement: Recent Progress and Challenges

B Pandey, AK Singh, SP Singh - … of Targeted Nano Drugs and Delivery …, 2019 - Elsevier
… for mimicking the role of the endogenous miRNA, which results in mRNA degradation/… , the
progress of miRNA therapeutics encountered many issues like in vivo introduction of miRNA

MicroRNA therapeutics and nucleic acid nano-delivery systems in bacterial infection: a review

Z Li, Z Lei, DB Cheng, T Sun - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
… acids are delivered through a nucleic acid delivery system to … Among the many nucleic acid
therapeutic ideas, microRNA, … advances in nucleic acid delivery systems and their clinical …

MicroRNA therapeutics: towards a new era for the management of cancer and other diseases

R Rupaimoole, FJ Slack - Nature reviews Drug discovery, 2017 - nature.com
… in the bloodstream and poor delivery to the target site of systemically delivered miRNA
mimics, as well as the clinical difficulties associated with local delivery, the initial studies resulted …

Recent progress in live cell mRNA/microRNA imaging probes based on smart and versatile nanomaterials

D He, KW Wong, Z Dong, HW Li - Journal of Materials Chemistry B, 2018 - pubs.rsc.org
… target mRNA/miRNA functional research. With the breakthrough in smart cell delivery techniques,
… In this review, we summarize different classes of state-of-the-art live cell miRNA/mRNA …

[HTML][HTML] Getting miRNA therapeutics into the target cells for neurodegenerative diseases: a mini-review

MM Wen - Frontiers in molecular neuroscience, 2016 - frontiersin.org
… of the innovative strategies employed to deliver miRNA into target cells. These viral and
non-viral carrier systems hold promise in RNA therapy delivery for neurodegenerative diseases. …

Non-viral based miR delivery and recent developments

AE Labatut, G Mattheolabakis - European Journal of Pharmaceutics and …, 2018 - Elsevier
… of the mature duplex miRNA, with the … progress of nanotechnology in the field of drug
delivery, and the prior, existing knowledge was quickly adjusted to meet the needs of miR delivery. …

[HTML][HTML] Functions of microRNA-33a/b and microRNA therapeutics

K Ono - Journal of cardiology, 2016 - Elsevier
… miR-33a/b and the progress in miRNA therapeutics for treatment of various diseases, …
delivery of siRNAs or miRNAs [29]. Liposome nanoparticles have been utilized for miRNA delivery