Strategies to use microRNAs as therapeutic targets
J Krützfeldt - Best practice & research Clinical endocrinology & …, 2016 - Elsevier
… to deliver miRNA mimics in vivo have made fast progress. … miRNA delivery also needs
further testing and is of much higher concern compared to miRNA inhibition since miRNA delivery …
further testing and is of much higher concern compared to miRNA inhibition since miRNA delivery …
MicroRNA-targeting nanomedicines for the treatment of intervertebral disc degeneration
… However, miR delivery encounters extracellular and intracellular biological barriers. A
promising technology to address this challenge is the vectorization of miRs within nanoparticles, …
promising technology to address this challenge is the vectorization of miRs within nanoparticles, …
Chondrocyte-targeted microRNA delivery by engineered exosomes toward a cell-free osteoarthritis therapy
Y Liang, X Xu, X Li, J Xiong, B Li, L Duan… - … applied materials & …, 2020 - ACS Publications
… progress in a rat model demonstrates the efficacy of this therapy. This work thereby showcases
a cell-free, organelle-based delivery … the intracellularly delivered miRNA mimic takes its …
a cell-free, organelle-based delivery … the intracellularly delivered miRNA mimic takes its …
Therapeutic implication of miRNA in human disease
A Walayat, M Yang, D Xiao - Antisense therapy, 2018 - books.google.com
… Some of the miRNA-based therapeutics are processed in preclinical and clinical trial for …
of miRNA-based therapeutics is how to increase the miRNA stability and optimize delivery …
of miRNA-based therapeutics is how to increase the miRNA stability and optimize delivery …
Encapsulation of miRNA and siRNA into Nanomaterials for Cancer Therapeutics
… In the present article, we discuss the latest developments in siRNA and miRNA drug delivery
… In this section, we center around an examination of the latest progress in the planning, …
… In this section, we center around an examination of the latest progress in the planning, …
Therapeutic prospects of microRNAs in cancer treatment through nanotechnology
R Awasthi, MJ Rathbone, PM Hansbro… - Drug delivery and …, 2018 - Springer
… potential of nanotechnology in miRNA formulation and delivery with particular emphasis on
… exploring the new vistas of miRNA delivery using nanotechnology in the cancer clinically. …
… exploring the new vistas of miRNA delivery using nanotechnology in the cancer clinically. …
Mechanisms of hydrogel-based microRNA delivery systems and its application strategies in targeting inflammatory diseases
S Hu, Y Liang, J Chen, X Gao… - Journal of Tissue …, 2024 - journals.sagepub.com
… the classification of miRNA hydrogel delivery systems, the basic … biomedical applications of
miRNA hydrogel delivery systems in … miRNA release, highlighting recent progress in miRNA …
miRNA hydrogel delivery systems in … miRNA release, highlighting recent progress in miRNA …
Lipid nanoparticles to deliver miRNA in cancer
… For example, neutral lipid emulsions (NLEs) have been investigated for miRNA delivery
in … for miRNA delivery into this organ. Trang et al. demonstrated that the delivery of miRNA-34 …
in … for miRNA delivery into this organ. Trang et al. demonstrated that the delivery of miRNA-34 …
Extracellular vesicles–advanced nanocarriers in cancer therapy: progress and achievements
T Huyan, H Li, H Peng, J Chen, R Yang… - International journal …, 2020 - Taylor & Francis
… This study further confirmed exosomes have superior ability to deliver either siRNA or shRNA
and suppress tumor growth in vivo. Citation32 miRNA is a type of noncoding RNA with a …
and suppress tumor growth in vivo. Citation32 miRNA is a type of noncoding RNA with a …
Synthetic SiRNA delivery: progress and prospects
TC Roberts, K Ezzat, S El Andaloussi… - SiRNA Delivery Methods …, 2016 - Springer
… successful delivery of high concentrations of exogenous SiRNAs may saturate the miRNA
… effective on-target silencing in vivo without perturbation of endogenous miRNA activity [36]. …
… effective on-target silencing in vivo without perturbation of endogenous miRNA activity [36]. …