Progress in the molecular pathogenesis and nucleic acid therapeutics for Parkinson's disease in the precision medicine era
… therapeutics in liver disease, where miRNA mimics or antimiRs may readily enter the … miRNA
delivery across the blood–brain barrier is one of the factors that limit the progress in miRNA-…
delivery across the blood–brain barrier is one of the factors that limit the progress in miRNA-…
[HTML][HTML] In vivo delivery and therapeutic effects of a microRNA on colorectal liver metastases
… progress to more favorable outcomes. Here, we report the effective delivery of an oligometastatic
microRNA (… Tumor-targeted microRNA miR-655-3p suppressed tumor growth when co-…
microRNA (… Tumor-targeted microRNA miR-655-3p suppressed tumor growth when co-…
Nanoparticle mediated RNA delivery for wound healing
… In order to aid in the progress of wound healing, white blood cells are initiated to the wound
… Viral vectors and synthetic miRNA mimics are two tools utilized to deliver miRNA sequences …
… Viral vectors and synthetic miRNA mimics are two tools utilized to deliver miRNA sequences …
Intracellular and extracellular microRNA: An update on localization and biological role
… However, miRNA is capable of entering mitochondria without ATP hydrolysis [185].
Therefore, mechanisms of AGO-miRNA delivery into mitochondria remains to be further clarified. …
Therefore, mechanisms of AGO-miRNA delivery into mitochondria remains to be further clarified. …
Development of microRNAs as potential therapeutics against cancer
N Abd-Aziz, NI Kamaruzman, CL Poh - Journal of oncology, 2020 - Wiley Online Library
… to overcome cancer growth, miRNA delivery, and approaches to … miRNA therapy in cancers
is to deliver miRNA antagonists or … progress has been made in establishing systemic miRNA …
is to deliver miRNA antagonists or … progress has been made in establishing systemic miRNA …
The potential of siRNA based drug delivery in respiratory disorders: Recent advances and progress
… , for safe and effective delivery. siRNA mediated pro-inflammatory gene or miRNA targeting
… conditions and thus providing sustained drug delivery, reduced therapeutic dose, and …
… conditions and thus providing sustained drug delivery, reduced therapeutic dose, and …
Micelleplexes as nucleic acid delivery systems for cancer-targeted therapies
M Pereira-Silva, I Jarak, C Alvarez-Lorenzo… - Journal of Controlled …, 2020 - Elsevier
… on the recent progress on the design of new micelleplex-based systems for NA delivery, the
… ], and co-delivery of tumor suppressor let-7b miRNA mimic and hedgehog pathway inhibitor …
… ], and co-delivery of tumor suppressor let-7b miRNA mimic and hedgehog pathway inhibitor …
[HTML][HTML] MicroRNA-based therapy in animal models of selected gastrointestinal cancers
J Merhautova, R Demlova, O Slaby - Frontiers in Pharmacology, 2016 - frontiersin.org
… pharmacological aspects of miRNA-based therapy with the emphasis on delivery systems,
and … The progress of screening techniques and computational stimulation may address bright …
and … The progress of screening techniques and computational stimulation may address bright …
The risks of miRNA therapeutics: in a drug target perspective
S Zhang, Z Cheng, Y Wang, T Han - Drug design, development …, 2021 - Taylor & Francis
… miRNA drugs (another therapeutic similar to siRNA drug). Here we report the existing obstacles
of miRNA … Citation29 Therefore, targeted drug delivery systems may eliminate or weaken …
of miRNA … Citation29 Therefore, targeted drug delivery systems may eliminate or weaken …
Reversing epigenetic mechanisms of drug resistance in solid tumors using targeted microRNA delivery
M Berman, G Mattheolabakis, M Suresh… - … on drug delivery, 2016 - Taylor & Francis
… Further, we consider how delivery of miRNA or … via miRNA delivery presents a novel
strategy for enhancing the efficacy of chemotherapeutics. Further, the ability to target delivery of …
strategy for enhancing the efficacy of chemotherapeutics. Further, the ability to target delivery of …