… (A) Transcription dynamics of endogenous and promoter-switched genes. Each panel …
To determine the drivers of transcription dynamics, we used cooccurrence matrices to assess …

… distinct role in bursting during transcriptional activation by γ-interferon. The CCAAT element
does not contribute significantly to the constitutive transcriptional dynamics of primary B-cells…

… TSS) on transcription dynamics in vivo. More precisely, we quantified two temporal aspects
of transcription, namely: 1) Synchrony, defined as the degree of inter-nuclear coordination in …

… static promoter architecture and dynamic feedback regulation coordinate transcriptional
burst kinetics on a genome-wide scale. Previous studies of transcriptional bursting were limited …

… DPE mutations dramatically change transcription dynamics throughout its expression domains,
… in converting enhancer activity into transcription dynamics during animal development. …

… and molecular memory in the promoter switching dynamics. Here we analytically solve a
gene … By analyzing the dynamical phase diagram of the system, we also find that molecular …

… are insufficient to describe the transcriptional dynamics of these latent HIV integrations in
the basal state and during TNF-mediated transcriptional activation. Moreover, stimulation of …

… communication regulates transcription dynamics. (A,B) Schematic for a biological model:
The upstream EP communication in the cell nucleus (A) guides the downstream transcription, …

… This expression is believed to be purely from the P2 promoter mediated by two enhancers:
a proximal enhancer located next to P2 29,34 and a distal shadow enhancer located 4.5 kb …

… Even though the analysis was indirect and approximate, it facilitated qualitative
measurements of promoter-mediated noise, as the system contained the single copy plasmid. …