The role of epigenetic dysregulation in suicidal behaviors
LM Fiori, G Turecki - Behavioral Neurobiology of Suicide and Self Harm, 2020 - Springer
… The first study investigating BDNF in suicide examined methylation of the promoter/exon
IV regions in the brain Wernicke area of people who died by suicide and found …
IV regions in the brain Wernicke area of people who died by suicide and found …
DNA methylation and hydroxymethylation and behavior
… hypermethylation in the promoter regions of ribosomal RNAs … a gene-specific increase of
DNA methylation downregulates … account for the pathophysiology observed the suicidal brain. …
DNA methylation downregulates … account for the pathophysiology observed the suicidal brain. …
Characterization of Cerebellum-Specific Ribosomal DNA Epigenetic Modifications in Alzheimer's Disease: Should the Cerebellum Serve as a Control Tissue After All?
TC Faria, HL Maldonado, LC Santos, R DeLabio… - Molecular …, 2020 - Springer
… methylation is the mechanism involved in rRNA expression regulation in AD. Hence, we
sought to explore the rDNA methylation pattern of two different brain … ribosomal RNA genes are …
sought to explore the rDNA methylation pattern of two different brain … ribosomal RNA genes are …
Epigenetic studies in suicidal ideation and behavior
… disorder and SCZ Discovered hypermethylation in the promoter region of the TrkB gene, as
well … of histone 3 Lysine 27 in the brains of suicide victims compared to non-suicide controls. …
well … of histone 3 Lysine 27 in the brains of suicide victims compared to non-suicide controls. …
Epigenetics of suicidal behaviors
LM Fiori, G Turecki - Alternatives to Suicide, 2020 - Elsevier
… They identified three regions that were differentially methylated in both brain areas, mapping
to the genes psoriasis susceptibility 1 candidate 3 (PSORS1C3), TAP binding protein (…
to the genes psoriasis susceptibility 1 candidate 3 (PSORS1C3), TAP binding protein (…
[HTML][HTML] Aberrant DNA Methylation of rDNA and PRIMA1 in Borderline Personality Disorder
S Teschler, J Gotthardt, G Dammann… - International journal of …, 2016 - mdpi.com
… Here, we analyzed DNA methylation patterns of the ribosomal RNA gene (rDNA promoter
… genes has been reported in the brain of suicide persons and this has been correlated with …
… genes has been reported in the brain of suicide persons and this has been correlated with …
Epigenomic Exploration of the Human Brain
TB Halene, G Hasler, A Mitchell… - Psychiatric Genetics: A …, 2018 - books.google.com
… methylation of the glucocorticoid receptor gene promoter NR3C1 and ribosomal DNA
repeats in the hippocampus of adult suicide … , methylation of the stress-sensitive gene FK506 …
repeats in the hippocampus of adult suicide … , methylation of the stress-sensitive gene FK506 …
Principles governing DNA methylation during neuronal lineage and subtype specification
… DNA methylation during brain development. (1) The program consists of three stages: an initial
… -wide methylation during progenitor proliferation is followed by loss of methylation during …
… -wide methylation during progenitor proliferation is followed by loss of methylation during …
[HTML][HTML] Overexpression of ribosomal RNA in the development of human cervical cancer is associated with rDNA promoter hypomethylation
H Zhou, Y Wang, Q Lv, J Zhang, Q Wang, F Gao… - PloS one, 2016 - journals.plos.org
… The possible relationship between expression and promoter methylation of rDNA has not …
we investigate rRNA gene expression by quantitative real time PCR, and promoter methylation …
we investigate rRNA gene expression by quantitative real time PCR, and promoter methylation …
A potential role for the noncoding transcriptome in psychiatric disorders
T Klengel - Harvard Review of Psychiatry, 2018 - journals.lww.com
… Ribosomal RNA (rRNA) genes have been found differentially methylated in postmortem
brain tissue of suicide … of protein synthesis in suicide. Transcribed ultraconserved regions are …
brain tissue of suicide … of protein synthesis in suicide. Transcribed ultraconserved regions are …