… -driven bone resorption, or is triggered independently, is not … tissue mechanical stress
influences new bone formation in … changes at the enthesis. In vitro investigation of the effects of IL-…

… cascades that drive pathological bone formation and may … by neutrophilic infiltration
surrounding the enthesis, the anatomic … mechanic stability can play a role in the new bone …

… enthesitis. The pathogenesis involves both an inflammatory process and … The role of
mechanical stress as the trigger of these … Likely, this bone formation is triggered by the …

… one characterized by new bone formation in synovial joints … of peripheral enthesitis with
reduction of mechanical strain. As … TNF-driven) and pathological new bone formation in JSpA. …

… with the coexistence of bone loss and new bone formation, both … model of ankylosing
enthesitis could not prevent it [43]. … Furthermore, the mechanical forces exert their effect on that …

… by which mechanical stress induces new bone formation … in human including enthesitis and
enthseal new bone formation was … in spondyloarthritis are driven by mechanical strain and …

… of function are caused by enthesitis, osteitis, synovitis and new bone formation.1 The … . Proof
of concept: enthesitis and new bone formation in spondyloarthritis are driven by mechanical …

… can induce enthesitis and new bone formation by acting on a … subchondral bone that is
exposed to high mechanical stress … monocyte progenitor (GMP)-driven haematopoiesis 109 . In a …

… Ankylosing spondylitis (AS), a subtype of spondyloarthritis (… of HLA-B27, and mechanical
loading stress to promote NBF. MIF … evidence that conventional DCs from HLA-B*27 tg rats drive …

… at spinal enthesis or peripheral enthesis with mechanically related or … TNF or IL-17 driven
immune systems activation are … potentially assisting in the new bone formation at the enthesis. …