… to minimizing friction and dissipation of mechanical energy. The concept of an ‘enthesis
organ’ recognizes that stress dissipation is not only the enthesis itself but also the surrounding …

… in order to dissipate mechanical stress. … enthesitis and in enthesal bone formation, highly
distinctive of SpA. Several hypotheses may explain why IL-23 has proven to be a potential new …

… These findings likely represent mechanically induced … enthesitis in psoriasis differs from
subclinical enthesitis in PsA, … ), whereas SpA-related new bone formation is difficult to assess in …

… It is postulated inflammation is initially triggered by mechanical stress or … enthesis through
NF-κB activation. Compared with previous studies, this study reported that new bone formation …

… , enthesitis (inflammation at sites of insertion of tendons and ligaments on bone) and new
bone formation … be that injury-associated bone repair differs from the mechanical type of bone …

… of the enthesitis of SpA was found to include the mechanical … stem cells and the formation
of new bone. Conclusion: It is a … the enthesitis and the formation of the new bone is indicated. …

… inflammation, whilst local bone formation occurs primarily at sites of enthesitis, where the
pro-… that mechanical stress may drive both entheseal inflammation and new bone formation in …

… Proof of concept: enthesitis and new bone formation in spondyloarthritis are driven by
mechanical strain and stromal cells. Ann Rheum Dis 2014;73:43745. doi:10.1136/annrheumdis-…

… Computed tomography-guided injections may be necessary for the sacroiliac joints, … -positive”
bone marrow edema is significantly associated with two findings: mechanical loading (eg, …

… of inflammation but not halter bone formation (57). Additionally… Inflammatory and mechanical
factors in the onset of enthesitis… mechanical forces may drive the onset of joint inflammation. …