Clinical significance of phospholipase A2 in glaucoma
… the protective role of … -specific inhibitors have been emerging as potential therapeutic
interventions to treat glaucoma. Those inhibitors are used as alternate strategies to replace steroids …
interventions to treat glaucoma. Those inhibitors are used as alternate strategies to replace steroids …
[PDF][PDF] Secretory phospholipase A2 group IIA: a potential therapeutic target in inflammation
AS Giresha - Current Research and Trends in Medical Science …, 2021 - researchgate.net
… However, effective and specific inhibitors of sPLA2GIIA are still not available to date. …
However, the protective inflammatory reactions become detrimental when the inflammatory …
However, the protective inflammatory reactions become detrimental when the inflammatory …
Phospholipase A2 as a modulator of infection, inflammation, and immunity
UN Das - Phospholipases in Physiology and Pathology, 2023 - Elsevier
… cells produce a specific combination of effector cytokines that bring about specific and distinct
… ) along with corticosteroids is recommended so that their (corticosteroids) antiinflammatory …
… ) along with corticosteroids is recommended so that their (corticosteroids) antiinflammatory …
[PDF][PDF] Amelioration of doxorubicin-Induced liver and kidney toxicities by nicorandil alone and co-administered with prednisolone and diltiazem
AJ Akindele, KI Amagon, GT Ekundayo… - Proceedings of the …, 2020 - researchgate.net
… calcium channel blocker/phospholipase A2 inhibitor did not elicit superior protective effect. …
The findings in this study in respect of ALT, a more specific liver enzyme, suggest that …
The findings in this study in respect of ALT, a more specific liver enzyme, suggest that …
[PDF][PDF] Effects of some calcium channel blockers againsts CCl 4-induced nephrotoxicity in albino rats
II Chinwe, UI Kingsley, EI Blessing - PhOL, 2019 - researchgate.net
… aim was to evaluate the protective effects of two selected calcium channel blockers (nifedipine
and … It further scientifically supports the potential use of calcium channel blockers for the …
and … It further scientifically supports the potential use of calcium channel blockers for the …
The phospholipase A2 superfamily: structure, isozymes, catalysis, physiologic and pathologic roles
… of corticosteroids to treat the inflammation [123]. … phospholipase A2 comprises a very diverse
collection of members, evolved to perform the same hydrolytic reaction in different specific …
collection of members, evolved to perform the same hydrolytic reaction in different specific …
Phospholipases A2
… human nonpancreatic secreted phospholipase A2 and a highly potent inhibitor (FPL67047XX). …
Inhibition of iPLA2 activity by specific inhibitor bromoenol lactone (BEL) reduced nicotine-…
Inhibition of iPLA2 activity by specific inhibitor bromoenol lactone (BEL) reduced nicotine-…
Phospholipase A2 Inhibitors of Marine Origin
TC Silva, DM Pereira, P Valentão… - Natural Products …, 2017 - Wiley Online Library
… Despite this, inflammatory processes play a protective role in … to inhibit calcium channels at
low concentrations with no effect on … activity, it is a non‐specific PLA2 inhibitor [57–61], due to …
low concentrations with no effect on … activity, it is a non‐specific PLA2 inhibitor [57–61], due to …
Lipoprotein-associated phospholipase A2 (Lp-PLA2) as a therapeutic target to prevent retinal vasopermeability during diabetes
P Canning, BA Kenny, V Prise… - Proceedings of the …, 2016 - National Acad Sciences
… BRB protection in diabetic rats through use of species-specific … Intravitreal injection of
antiinflammatory corticosteroids has … parenchyma, suggesting a protective effect of BBB function …
antiinflammatory corticosteroids has … parenchyma, suggesting a protective effect of BBB function …
[PDF][PDF] Role of oxidative stress and calcium regulation in Duchenne muscular dystrophy: pharmacological investigations
H ISMAIL - Citeseer
… The first was doxorubicin which inhibited phospholipase A2 … as diapocynin showed a
protective effect; this was probably … In contrast, the prednisone derivative deflazacort appears to …
protective effect; this was probably … In contrast, the prednisone derivative deflazacort appears to …