Psoriasis as an immune-mediated and inflammatory systemic disease: from pathophysiology to novel therapeutic approaches

A Campanati, A Marani, E Martina, F Diotallevi, G Radi… - Biomedicines, 2021 - mdpi.com
… in psoriasis considered as a systemic inflammatory disease? … association between multiple
sclerosis and psoriasis, an … The pathogenetic mechanism is unclear; however, a recent …

Psoriasis and systemic inflammatory disorders

T Tashiro, Y Sawada - International journal of molecular sciences, 2022 - mdpi.com
… concerns which kinds of therapeutic options are better to regulate the development of systemic
inflammatory disorders. In the underlying mechanism of psoriasis, TNF-α or IL-23 are the …

Management of psoriasis as a systemic disease: what is the evidence?

NJ Korman - British Journal of Dermatology, 2020 - academic.oup.com
… symptoms but also reduce systemic inflammation, hence … the pathophysiological relationship
between psoriasis and its … effects of systemic inflammation in moderate‐to‐severe plaque …

Systemic immune mechanisms in atopic dermatitis and psoriasis with implications for treatment

E Guttman‐Yassky, JG Krueger… - Experimental …, 2018 - Wiley Online Library
Links between psoriasis and systemic inflammation are clinically well recognized and …
biomarkers of systemic inflammation may provide a mechanism for the treatment of psoriasis and …

Chronic inflammation as the underlying mechanism of the development of lung diseases in psoriasis: a systematic review

M Mleczko, A Gerkowicz, D Krasowska - International Journal of …, 2022 - mdpi.com
Psoriasis is a systemic inflammatory disease caused by dysfunctional interactions between
the innate and adaptive immune responses. The systemic inflammation in psoriasis may be …

Psoriasis and inflammatory bowel disease: links and risks

C Vlachos, G Gaitanis, KH Katsanos… - Psoriasis: Targets …, 2016 - Taylor & Francis
links, and therapeutic strategies for psoriasis and IBD is presented. Specific emphasis is
placed on the role of the immune cell species and inflammatory … of the mechanistically more …

[HTML][HTML] Systemic inflammation and cardiovascular comorbidity in psoriasis patients: causes and consequences

WH Boehncke - Frontiers in immunology, 2018 - frontiersin.org
… on epidemiologic, genetic, and mechanistic studies that analyzed the relation between
link between psoriasis and cardiovascular disease via metabolic factors, the only direct link the …

The pathophysiological mechanisms and the quest for biomarkers in psoriasis, a stress‐related skin disease

M Tampa, MI Sarbu, MI Mitran, CI Mitran… - Disease …, 2018 - Wiley Online Library
… the assessment of the severity of psoriasis. We aim to review the … in psoriasis, focusing on
the most critical advances in psoriasisconditions, thus emphasizing the relationship between

The risk of systemic diseases in those with psoriasis and psoriatic arthritis: from mechanisms to clinic

YR Woo, CJ Park, H Kang, JE Kim - International Journal of Molecular …, 2020 - mdpi.com
… versa, the possible underlying mechanism of action between … to reduce the systemic
inflammation of psoriasis, we can … the development of various autoimmune disorders. However, to …

[HTML][HTML] Role of skin and gut microbiota in the pathogenesis of psoriasis, an inflammatory skin disease

DK Hsu, MA Fung, HL Chen - Medicine in Microecology, 2020 - Elsevier
… microbiome play key roles in the pathogenesis of psoriasis. The aim of this review is to
identify a link between the microbial ecology of the gut and skin, and their relevance to psoriasis. …