[图书][B] Quantitative Analysis of the Effects of Environmental Factors On Lifespan and Stress Resistance of C. Elegans

JH Ramirez - 2022 - search.proquest.com
… a new interaction of DAF-16 in the cell nucleoli, where we observed DAF-16 migration, …
elegans, the DAF-16 transcription factor is a key aging regulator that governs the Insulin/IGF-1 …

The silencing of ets-4 mRNA relies on the functional cooperation between REGE-1/Regnase-1 and RLE-1/Roquin-1

D Sobańska, AA Komur, A Chabowska-Kita… - Nucleic acids …, 2022 - academic.oup.com
Caenorhabditis elegans ortholog of Regnase-1, we have uncovered its functional relationship
with RLE-1, … the ets-4 decay, RLE-1 could regulate additional mRNAs independently from …

[PDF][PDF] as a model for aging research

HID Mack, T Heimbucher, CT Murphy - reproduction, 2018 - serc.carleton.edu
Caenorhabditis elegans is a key model system for experimental research on the genetic
regulation of aging… ] in daf-2, wild-type, and daf-16;daf-2 mutants have identified tissue-specific …

[PDF][PDF] The C. elegans “hibernation”: surviving cold through ferritin-mediated iron detoxification

A Komur - portal.ichb.pl
… of longevity by E3 (RLE-1) that ubiquitinates DAF-16 directing it … Importantly for this research,
DAF-16 was described to regulateelegans seems to stop aging while exposed to the cold, …

An mRNA silencing mechanism reliant on the cooperation between REGE-1/Regnase-1 and RLE-1/Roquin-1

D Sobańska, AA Komur, A Chabowska-Kita, J Gumna… - bioRxiv, 2021 - biorxiv.org
… Recently, we characterized the Caenorhabditis elegans ortholog of Regnase-1, which we …
that might be regulated independently of RLE-1. Conversely, RLE-1 is likely to regulate other …

Regulation of the Heat Shock Response via Lysine Acetyltransferase CBP-1 and in Neurodegenerative Disease in Caenorhabditis elegans

LN Barrett - 2022 - search.proquest.com
… The decline of proteostasis is a hallmark of aging that is, in part, … aging are largely unknown.
In this study, we examined lysine acetyltransferase regulation of the HSR and HSF-1 in C. …

Toxic effects induced by nonylphenol (NP) and ethoxylated nonylphenol (NP-9) in Caenorhabditis elegans

AC De la Parra Guerra - 2020 - repositorio.unicartagena.edu.co
… NP y NP-9 indujeron la activación y la translocación nuclear de DAF-16, lo que sugiere
que la transcripción de los genes de respuesta al estrés puede estar mediada por la vía de …

Sirtuins, epigenetics and longevity

M Wątroba, I Dudek, M Skoda, A Stangret… - Ageing research …, 2017 - Elsevier
… involved in the cell metabolism and can regulate many cellular functions including DNA repair,
… Ubiquitylation of DAF-16 which is the ortholog of the FOXO family in C. elegans leads to a …

[引用][C] 21 Mitochondrial Oxidative Stress

DF Dai - Aging: Exploring a Complex Phenomenon, 2017 - CRC Press

A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin

A Sgromo, T Raisch, P Bawankar, D Bhandari… - Nature …, 2017 - nature.com
… in bulk mRNA degradation by catalysing the removal of mRNA poly(A) … Caenorhabditis
elegans homologue of Roquin1, RLE-1, (regulation of longevity by E3) exhibit E3 ubiquitin ligase