ROCK2 regulates monocyte migration and cell to cell adhesion in vascular endothelial cells
Y Takeda, K Matoba, D Kawanami, Y Nagai… - International journal of …, 2019 - mdpi.com
… Activation of the Rho/ROCK pathway leads to the phosphorylation of downstream substrates…
that ROCK2 deficiency in bone marrow-derived cells showed substantially reduced lipid …
that ROCK2 deficiency in bone marrow-derived cells showed substantially reduced lipid …
ROCK as a therapeutic target for ischemic stroke
… single and double deficiency of ROCK1 and ROCK2 lead to … more rapidly, leading to
decreased cerebral injury and lower … Bone marrow-derived ROCK1-deficient macrophages have …
decreased cerebral injury and lower … Bone marrow-derived ROCK1-deficient macrophages have …
Decreased thromboembolic stroke but not atherosclerosis or vascular remodelling in mice with ROCK2-deficient platelets
N Sladojevic, GT Oh, HH Kim… - Cardiovascular …, 2017 - academic.oup.com
… heart, monocytes, or other bone marrow-derived cells (n = 5, Figure 1… Because ROCK2
deficiency in platelets leads to decreased … cholesterol transport and cholesterol efflux, 34 ROCK2-…
deficiency in platelets leads to decreased … cholesterol transport and cholesterol efflux, 34 ROCK2-…
Context-dependent signalling in platelets in vascular diseases: ROCK2 around thrombosis
JG Filep - Cardiovascular Research, 2017 - academic.oup.com
… An unexpected observation in this study was the failure of ROCK2-deficient platelets to …
deficiency in bone marrow-derived cells leads to increased cholesterol efflux and decreased …
deficiency in bone marrow-derived cells leads to increased cholesterol efflux and decreased …
Targeting ROCK signaling in health, malignant and non-malignant diseases
R Shahbazi, B Baradaran, M Khordadmehr, S Safaei… - Immunology letters, 2020 - Elsevier
… which apoptosis has been decreased in the cardiac cells [26]… -activated receptor-g-dependent
cholesterol efflux [32]. Fig. 3 … mutations in ROCK2 can lead to increased kinase activity [9]. …
cholesterol efflux [32]. Fig. 3 … mutations in ROCK2 can lead to increased kinase activity [9]. …
[PDF][PDF] Association of moderate aerobic exercise and rho-associated kinase 2 concentration in subjects with dyslipidemia
H Bai, J Sun, G Du, F Jiao - Archives of Medical Science, 2017 - termedia.pl
… lowering induced by moderate aerobic exercise may have led to reduced leukocyte ROCK2
… deficiency in bone marrowderived cells leads to increased cholesterol efflux and decreased …
… deficiency in bone marrowderived cells leads to increased cholesterol efflux and decreased …
Pathophysiological effects of RhoA and Rho-associated kinase on cardiovascular system
A Cai, L Li, Y Zhou - Journal of Hypertension, 2016 - journals.lww.com
… similarity, the pathophysiological roles of ROCK1 and ROCK2 … of ROCK1 in bone
marrow-derived cells retards … AI-mediated cholesterol efflux, thus favoring foam cells formation …
marrow-derived cells retards … AI-mediated cholesterol efflux, thus favoring foam cells formation …
Rho/Rho Kinase Signaling Pathway and Disease: from Bed to Bench
Y Wang, Y Zhang, D Zhang - Frontiers in Cardiovascular Drug …, 2022 - books.google.com
… to make and can potentially lead to … , bone marrow–derived cells of Rock2 deletion or
haploinsufficiency transplantation into Ldlr −/− mice also protects from atherosclerosis and reduces …
haploinsufficiency transplantation into Ldlr −/− mice also protects from atherosclerosis and reduces …
[PDF][PDF] ROCK2 Regulates Monocyte Migration and Cell to Cell Adhesion in Vascular Endothelial Cells.
竹田裕介 - International journal of molecular sciences, 2021 - ir.jikei.ac.jp
… Activation of the Rho/ROCK pathway leads to the phosphorylation of downstream substrates…
that ROCK2 deficiency in bone marrow-derived cells showed substantially reduced lipid …
that ROCK2 deficiency in bone marrow-derived cells showed substantially reduced lipid …
ROCK inhibition may stop diabetic kidney disease
K Matoba, Y Takeda, Y Nagai, Y Kanazawa… - JMA journal, 2020 - jstage.jst.go.jp
… to impaired closure of the eyelids and umbilical ring in mice (6), whereas ROCK2 deficiency
… deficiency in bone marrow-derived cells leads to increased cholesterol efflux and decreased …
… deficiency in bone marrow-derived cells leads to increased cholesterol efflux and decreased …