… the search terms ((novel psychoactive substance) OR new psychoactive substance) AND
(“2015/… Biotransformation studies performed in vitro with and without confirmation in authentic …

… the metabolism of new psychoactive substances for toxicological screening purposes - A …
fingerprinting of new psychoactive substances (NPS): What can we learn from in vitro data? …

… As part of this work, the EMCDDA monitors more than 620 new psychoactive substances
that have appeared on Europe's drug market over the past 20 years. Data on these substances …

… such as NPS are mixed with the more commonly used recreational drugs (Brunt et al., 2017).
Toxicological and forensic analyses are crucial to combat such phenomena: efforts towards …

… of novel psychoactive substances, otherwise known as" legal highs." The book covers individual
classes of novel psychoactive substances … of the pharmacology of the substance and a …

… The term new psychoactive substance is a legal definition … Traditionally established recreational
drugs and NPS have been … and prescription drugs, increasing the risk of drug toxicity or …

… tryptamines, indolalkylamines, new synthetic opioids, … psychoactive drugs of natural origin
and synthetic molecules. Previous studies have been limited to the analytical and toxicological …

… /SERT) inhibition ratio with relevance to clinical toxicity. The ratio derived from in vitro binding
studies help to predict clinical toxicity of novel substances. A low DAT/SERT inhibition ratio …

… NPS are usually derivatives or analogues of classical recreational drugs designed to imitate
… limitations of analytical screening in managing patients presenting with acute NPS toxicity. …

… Even though the in vitro efficacy and potency of several new compounds, such as AP-237, …
to additional toxicity due to serotonin syndrome, especially in combination with other drugs …